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胆囊癌中13组淋巴结的难题:与一个被遗忘实体的回顾性尝试

Conundrum of station 13 lymph nodes in Gallbladder Carcinoma: Retrospective tryst with a forgotten entity.

作者信息

Tripathi Mayank, Vineet Kumar, Joshi Nitesh, Pal Ankita, Vispute Tejas, Kapoor Akhil, Paul Paramita

机构信息

Department of Surgical Oncology, MPMMCC & HBCH, Tata Memorial Centre, Homi Bhabha National Institute, Varanasi, India.

Clinical Research Secretariat, MPMMCC & HBCH, Tata Memorial Centre, Homi Bhabha National Institute, Varanasi, India.

出版信息

Updates Surg. 2025 May 13. doi: 10.1007/s13304-025-02237-7.

Abstract

Gallbladder cancers are one of the lethal cancers with dismal prognosis. There is discrepancy between various biliary societies regarding extent of regional lymph nodes of gallbladder. Some consider station 13 as regional nodes, whereas others consider it as distant metastatic node. This is a retrospective analysis of disease-free survival of stage IIIB and IVB-M0 patients in gall bladder cancer with positive station 13 lymph node. Electronic medical records of patients were used to retrieve the data. The mean and median disease-free survival of gallbladder carcinoma patients with station 13 lymph-node positivity is 16.2 months (95% CI 11.57-20.85 months) and 12 months (95% CI 9.57-14.43 months), respectively. Disease-free survival of Stage IIIB and IVB-M0 gallbladder carcinoma patients with station 13 lymph-node positivity is better than overall survival of stage IVB-M1 patients and supports the inclusion of station 13 lymph node as regional lymph-nodal basin of gall bladder carcinoma. This study paves the way for a large prospective study to consider station 13 lymph node as regional lymph node in gallbladder cancer.

摘要

胆囊癌是预后极差的致命性癌症之一。不同的胆道协会对于胆囊区域淋巴结的范围存在分歧。一些人认为第13组淋巴结属于区域淋巴结,而另一些人则认为它是远处转移淋巴结。这是一项对伴有第13组淋巴结阳性的IIIB期和IVB-M0期胆囊癌患者无病生存期的回顾性分析。利用患者的电子病历检索数据。伴有第13组淋巴结阳性的胆囊癌患者的平均和中位无病生存期分别为16.2个月(95%可信区间11.57 - 20.85个月)和12个月(95%可信区间9.57 - 14.43个月)。伴有第13组淋巴结阳性的IIIB期和IVB-M0期胆囊癌患者的无病生存期优于IVB-M1期患者的总生存期,支持将第13组淋巴结纳入胆囊癌区域淋巴结区域。本研究为一项大型前瞻性研究铺平了道路,该研究将考虑把第13组淋巴结作为胆囊癌的区域淋巴结。

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