Królak-Ulińska Aneta, Religioni Urszula, Chełstowska Beata, Panford-Quainoo Edwin, Doniec Zbigniew, Vaillancourt Regis, Merks Piotr
Anesthesiology and Intensive care Unit, Węgrów Regional Hospital, Węgrów, Poland.
School of Public Health, Centre of Postgraduate Medical Education, Warsaw, Poland.
Med Pharm Rep. 2025 Apr;98(2):176-182. doi: 10.15386/mpr-2740. Epub 2025 Apr 29.
The irrational use of antibiotics is one of the biggest threats to public health, as recently highlighted in the documents from the World Health Organization. It includes both the choice of an inappropriate drug, dose, form, or length of therapy for the patient, and a lack of attention to the global cost of treatment. One of the effects of excessive and irrational use of antibiotics worldwide is the increasing number of antibiotic-resistant microorganisms. The growing number of bacterial illnesses and deaths caused by this type of pathogens is of great significance, making the consequences of incorrect antibiotic use both medical and economic. In the rationalization of pharmacotherapy, the significant role of medical staff, including pharmacists, who have extensive knowledge in the field of antibiotic therapy, is emphasized. The main goal of the rational management of antimicrobial drugs should be to improve patient treatment outcomes and minimize the medical and economic consequences of antibiotic use. Antibiotic therapy rationalization programs are needed in all healthcare facilities, both in open care and in hospital settings. Educational interventions that target primary care physicians and physicians prescribing antibiotics in hospitals are necessary. Additionally, pharmacists, being the most accessible healthcare workers, can build awareness of rational antibiotic therapy among patients.
抗生素的不合理使用是对公众健康的最大威胁之一,世界卫生组织的文件最近强调了这一点。它既包括为患者选择不适当的药物、剂量、剂型或治疗时长,也包括对全球治疗成本缺乏关注。全球范围内过度和不合理使用抗生素的后果之一是产生抗生素耐药性微生物的数量不断增加。由这类病原体导致的细菌性疾病和死亡数量不断增加,这具有重大意义,使得抗生素使用不当的后果在医学和经济方面都很严重。在药物治疗合理化过程中,强调了包括药剂师在内的医务人员的重要作用,他们在抗生素治疗领域拥有广泛知识。抗菌药物合理管理的主要目标应该是改善患者的治疗效果,并将抗生素使用的医学和经济后果降至最低。所有医疗机构,无论是门诊还是住院环境,都需要抗生素治疗合理化项目。针对初级保健医生和在医院开具抗生素处方的医生进行教育干预是必要的。此外,药剂师作为最容易接触到的医护人员,可以提高患者对合理使用抗生素治疗的认识。