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2019冠状病毒病与营养之间的动态联系:基于机器学习和文献计量分析的益生菌视角综述

The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis.

作者信息

Stefanis Christos, Tsigalou Christina, Bezirtzoglou Ioanna, Mitropoulou Gregoria, Voidarou Chrysoula, Stavropoulou Elisavet

机构信息

Laboratory of Hygiene and Environmental Protection, Department of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

School of Chemistry, University of Edinburgh, Edinburgh, United Kingdom.

出版信息

Front Nutr. 2025 May 9;12:1575130. doi: 10.3389/fnut.2025.1575130. eCollection 2025.

Abstract

INTRODUCTION

The pandemic crisis is now a memorable milestone in the history of science, not only for the impacts on the population's health but also for the effort of the medical community to find immediate solutions amid the pandemic so that appropriate therapeutic means can be provided. Diet and nutrition could not fail to be studied in the context of combating the side effects of COVID-19. This study attempts to detect the relationship between dietary patterns and the disease of COVID-19 and emphasizes research on probiotics by mapping the knowledge produced during the pandemic until 2024.

METHODS

In addition to bibliometrics, a machine-learning framework, ASReview, was used to structure the literature search. With this method, 2,309 articles were collected from the PubMed database, with 599 constituting inputs into bibliometric software and further analysis.

RESULTS

Food choices, dietary patterns, vitamins and their role (vitamin D), obesity, and probiotics were keywords that attracted global research attention. Dietary supplements also constituted a field of study regarding the evolution of the disease and the impact they could have after the first pandemic wave.

DISCUSSION

Probiotics were considered an adjunct therapeutic intervention not only during the period before the development of vaccines but also alongside other therapeutic solutions. Whether used preventively or during the treatment phase, probiotics were studied to combat COVID-19 due to their potential role in immunomodulation and ability to regulate gut microbiota during respiratory infections.

摘要

引言

这场大流行危机如今已成为科学史上一个值得铭记的里程碑,这不仅是因为它对民众健康产生了影响,还因为医学界在大流行期间努力寻找即时解决方案,以便能够提供适当的治疗手段。在抗击新冠病毒19(COVID-19)副作用的背景下,饮食和营养研究势在必行。本研究试图检测饮食模式与COVID-19疾病之间的关系,并通过梳理截至2024年大流行期间产生的知识,强调对益生菌的研究。

方法

除了文献计量学,还使用了一个机器学习框架ASReview来构建文献检索。通过这种方法,从PubMed数据库收集了2309篇文章,其中599篇作为文献计量软件的输入数据并进行进一步分析。

结果

食物选择、饮食模式、维生素及其作用(维生素D)、肥胖和益生菌是吸引全球研究关注的关键词。膳食补充剂也是关于疾病演变及其在第一波大流行后可能产生的影响的一个研究领域。

讨论

益生菌不仅在疫苗研发之前被视为一种辅助治疗干预措施,而且在其他治疗方案中也被视为辅助措施。由于益生菌在免疫调节方面的潜在作用以及在呼吸道感染期间调节肠道微生物群的能力,无论是预防性使用还是在治疗阶段使用,都对其进行了研究以对抗COVID-19。

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