Vongelis Pavlos, Koulouris Nikolaos G, Bakakos Petros, Rovina Nikoletta
Respiratory Function Laboratory, 1st Department of Respiratory Medicine, Sotiria Hospital, Medical School, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.
Int J Environ Res Public Health. 2025 Apr 30;22(5):709. doi: 10.3390/ijerph22050709.
Air pollution is a significant and widespread issue that presents serious challenges for both human health and the environment because of the presence of a variety of harmful substances in the air, such as tropospheric ozone (O), particulate matter (PM), nitrogen oxides (NOx), sulfur dioxide (SO), and carbon monoxide (CO). In this research, the aim is to evaluate the current evidence for the harmful effects of air pollution on human health, focusing on tropospheric ozone, and to highlight the need for further research in the future. The objective is to evaluate recent data on the respiratory and cardiovascular risks caused by air pollution, the potential association between climate change due to air pollution and human disorders, and the subsequent economic burden. A systematic search of the literature is conducted using PubMed, Scopus, Web of Science, and regulatory reports (EPA), focusing on peer-reviewed studies, epidemiological analyses, and clinical and experimental studies. The key findings indicate that O exposure contributes to inflammatory lung injury and to the worsening of preexisting conditions like asthma and COPD, is associated with cancer, and also has numerous negative impacts on neurological, metabolic, and reproductive health, combined with increased healthcare costs. These findings highlight the significance of O pollution as a major public health concern, emphasizing the need for immediate measures to decrease emissions and effective policies to protect the climate and the health of the individuals.
空气污染是一个重大且普遍存在的问题,由于空气中存在各种有害物质,如对流层臭氧(O)、颗粒物(PM)、氮氧化物(NOx)、二氧化硫(SO)和一氧化碳(CO),它对人类健康和环境都构成了严峻挑战。在本研究中,目的是评估空气污染对人类健康有害影响的现有证据,重点关注对流层臭氧,并强调未来进一步研究的必要性。目标是评估近期关于空气污染导致的呼吸和心血管风险的数据、空气污染导致的气候变化与人类疾病之间的潜在关联以及随之而来的经济负担。使用PubMed、Scopus、科学网和监管报告(美国环境保护局)对文献进行系统检索,重点关注同行评审研究、流行病学分析以及临床和实验研究。主要研究结果表明,接触臭氧会导致肺部炎症损伤,并使哮喘和慢性阻塞性肺疾病等现有病情恶化,与癌症有关,还对神经、代谢和生殖健康有诸多负面影响,同时增加了医疗成本。这些发现凸显了臭氧污染作为一个主要公共卫生问题的重要性,强调需要立即采取措施减少排放,并制定有效的政策来保护气候和个人健康。