韩国的细颗粒物、自杀与城市化：一项全国性时间分层病例交叉研究。
Fine particulate matter, suicide, and urbanicity in South Korea: A nationwide time-stratified cases-crossover study.
作者信息
Kim RyangHa, Oh Jieun, Min Harin, Ahn Seoyeong, Kim Yejin, Kim Ayoung, Kang Cinoo, Kwon Dohoon, Park Jinah, Kim Ho, Kim Yoonhee, Lee Whanhee
机构信息
Graduate School of Data Science, KAIST, Daejeon, South Korea.
Department of Public Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea.
出版信息
iScience. 2025 Apr 22;28(5):112506. doi: 10.1016/j.isci.2025.112506. eCollection 2025 May 16.
Previous studies reported a link between exposure to ambient fine particulate matter (PM) and suicide. However, due to the lack of data from unmonitored areas, it has been difficult to assess heterogeneous impacts of PM by urbanicity. This case-crossover study investigated the relationship between short-term PM and suicide (2015-2019). In the overall population (65,634 suicide deaths), PM was marginally associated with suicide risk (odds ratio [OR]: 1.008, 95% confidence interval [CI]: 0.997-1.020). However, the association was stronger in rural areas (OR: 1.044, 95% CI: 0.996-1.095) and individuals aged 0-44 years (OR: 1.025, 95% CI: 1.002-1.048) compared to metropolitan/urban areas and older age groups. Metropolitan women aged 45-64 years (OR: 1.067, 95% CI: 1.013-1.124) and rural men aged 0-44 years (OR: 1.129, 95% CI: 0.988-1.289) showed the highest OR estimates than other subpopulations. These findings provide evidence to support more targeted suicide intervention strategies.
先前的研究报告了暴露于环境细颗粒物（PM）与自杀之间的联系。然而，由于缺乏来自未监测地区的数据，一直难以评估按城市化程度划分的PM的异质性影响。这项病例交叉研究调查了短期PM与自杀之间的关系（2015 - 2019年）。在总体人群（65,634例自杀死亡）中，PM与自杀风险存在微弱关联（优势比[OR]：1.008，95%置信区间[CI]：0.997 - 1.020）。然而，与大城市/城市地区和老年人群体相比，农村地区（OR：1.044，95% CI：0.996 - 1.095）以及0 - 44岁的个体（OR：1.025，95% CI：1.002 - 1.048）中的关联更强。45 - 64岁的大城市女性（OR：1.067，95% CI：1.013 - 1.124）和0 - 44岁的农村男性（OR：1.129，95% CI：0.988 - 1.289）的OR估计值高于其他亚人群。这些发现为支持更具针对性的自杀干预策略提供了证据。
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