Ajebli Mohammed, Amssayef Ayoub, Sabiri Maryame, Radi Fatima Zahrae, Bouhlali Eimad Dine Tariq, Eddouks Mohamed
Faculty of Sciences and Tecniques Errachidia, Moulay Ismail University, Meknes 11201, Morocco.
Laboratory of Biotechnology, Conservation and Valorization of Bioressources (BCVB), Research Unit: Api-Phytotherapy, Physiology, Environnement and Health, Department of Biology, Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, Fez 30003, Morocco.
Plants (Basel). 2025 May 24;14(11):1606. doi: 10.3390/plants14111606.
() is a medicinal plant that is traditionally used to treat various health conditions, including diabetes, constipation, diarrhea, and other digestive issues. However, comprehensive analysis of its traditional uses, phytochemistry, and pharmacological applications is still lacking. This review aims to systematically consolidate available information on the ethnopharmacological relevance, chemical profiles, and pharmacological activities of . A comprehensive literature review of was conducted across multiple scientific databases. Based on predefined inclusion criteria (full-text English publications providing relevant data on ) and exclusion criteria (abstracts only, studies on other species), 29 relevant studies were selected. This review systematically integrated traditional ethnobotanical knowledge with modern scientific insights, analyzing phytochemical compositions, biological activities, and pharmacological potential through a methodology designed to ensure unbiased selection from diverse sources. Traditional uses of include treatments for diabetes, gastrointestinal disorders, snake bites, dehydration, and burns. Phytochemical studies revealed a wealth of polyphenols, flavonoids, tannins, glycosides, terpenoids, and sesquiterpenoids. In vitro and in vivo assays showed antibacterial, antifungal, anti-inflammatory, antidiabetic, antihypertensive, cytotoxic, and antioxidant properties. There are insufficient toxicity studies to assess the safety of this species. However, pharmacological research on this species remains limited. This review is the first to synthesize the traditional uses, phytochemistry, and biological activities of , highlighting its pharmacological potential. However, further comprehensive research, including clinical trials, toxicological evaluations, and mechanistic studies, is necessary to fully identify active compounds and confirm their therapeutic applications, thus warranting additional investigation into this medicinal herb's complete benefits.
()是一种药用植物,传统上用于治疗各种健康问题,包括糖尿病、便秘、腹泻和其他消化问题。然而,对其传统用途、植物化学和药理应用的全面分析仍然缺乏。本综述旨在系统整合有关()的民族药理学相关性、化学概况和药理活性的现有信息。在多个科学数据库中对()进行了全面的文献综述。根据预定义的纳入标准(提供有关()相关数据的英文全文出版物)和排除标准(仅摘要、对其他物种的研究),选择了29项相关研究。本综述系统地将传统民族植物学知识与现代科学见解相结合,通过一种旨在确保从不同来源进行无偏选择的方法,分析植物化学成分、生物活性和药理潜力。()的传统用途包括治疗糖尿病