Elyasinia Fezzeh, Pourfaraji Seyed Morteza, Abbasi Mohammadmahdi, Soroush AhmadReza, Eslamian Reza, Kiani Fakhrodin, Mir Ali, Mohammadzadeh Narjes
Department of Surgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of General Surgery, School of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, End of Keshavarz Blvd., Tehran, 1419733141, Iran.
BMC Surg. 2025 Jul 3;25(1):279. doi: 10.1186/s12893-025-03009-1.
The prevalence of impaired health-related quality of life (HRQOL) and some mental health complications, such as anxiety and depression, were previously reported to be higher in cases with obesity. However, the prevalence and changes before and after metabolic bariatric surgery (MBS) are less well-defined in various populations of individuals with severe obesity.
In this prospective study, the status of HRQOL, anxiety, and depression symptoms of 32 cases with severe obesity who underwent sleeve gastrectomy (SG) were investigated one month before and one year after surgery. The assessments were performed through the Hospital Anxiety and Depression Scale (HADS) and the Impact of Weight on Quality of Life-lite (IWQOL-Lite) questionnaires.
One year after surgery, Patients' average body mass index (BMI) decreased significantly by 9.14 kg/m (95% CI: -10.76; -7.52. At baseline, the incidence rates of probable/possible anxiety or depression disorders were 65.6% and 46.9%, respectively. However, these symptoms did not improve significantly after surgery. In contrast, HRQOL scores significantly improved across all domains.
The point prevalence of mental health complications appears to be relatively higher among patients who underwent MBS compared to the general population. While the surgery effectively reduced weight and improved the HRQOL of patients, the impact on anxiety and depression was insignificant. Due to the small sample size, especially the limited number of patients with abnormal HADS scores, these findings should be interpreted cautiously.
先前有报道称,肥胖患者中与健康相关的生活质量受损(HRQOL)以及一些心理健康并发症,如焦虑和抑郁的患病率较高。然而,在重度肥胖的不同人群中,代谢性减肥手术(MBS)前后这些情况的患病率及变化尚不明确。
在这项前瞻性研究中,对32例行袖状胃切除术(SG)的重度肥胖患者在术前1个月和术后1年进行HRQOL、焦虑和抑郁症状状况的调查。评估通过医院焦虑抑郁量表(HADS)和体重对生活质量的影响-简化版(IWQOL-Lite)问卷进行。
术后1年,患者的平均体重指数(BMI)显著下降9.14kg/m²(95%CI:-10.76;-7.52)。基线时,可能/疑似焦虑或抑郁障碍的发生率分别为65.6%和46.9%。然而,术后这些症状并未显著改善。相比之下,HRQOL评分在所有领域均显著改善。
与普通人群相比,接受MBS的患者中心理健康并发症的时点患病率似乎相对较高。虽然手术有效减轻了患者体重并改善了HRQOL,但对焦虑和抑郁的影响不显著。由于样本量小,尤其是HADS评分异常的患者数量有限,这些发现应谨慎解读。