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Editorial: Post-translational modifications in human cancer: pharmacological insights and therapeutic opportunities.

作者信息

Chen Yongzhi, Fan Angelina W, Huang Lei

机构信息

Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Westborough, MA, United States.

Westborough High School, Westborough, MA, United States.

出版信息

Front Pharmacol. 2025 Jul 7;16:1654659. doi: 10.3389/fphar.2025.1654659. eCollection 2025.

Abstract
摘要

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The impact of dysregulation SUMOylation on prostate cancer.
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Post-translational modifications and their implications in cancer.
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Advances in post-translational modifications of proteins and cancer immunotherapy.
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Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation.
Cell. 2023 Aug 31;186(18):3945-3967.e26. doi: 10.1016/j.cell.2023.07.013. Epub 2023 Aug 14.
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PRMT5 activates AKT via methylation to promote tumor metastasis.
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Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review.
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