Suppr超能文献

揭示高血压患者的心理健康负担:探究三级护理医院中接受治疗患者的心理困扰、认知功能及其对生活质量的影响。

Unmasking the Mental Health Burden of Hypertension: Examining Psychological Distress, And Cognitive Function, Impact on Quality of Life in Patients Undergoing Treatment in a Tertiary Care Hospital.

作者信息

Fatima Maham, Aslam Adeel, Ijaz Maheen, Anwar Mudassir, Jamshed Shazia, Asiri Saeed, Syed Wajid

机构信息

Faculty of Pharmacy, University of Lahore, Lahore, Pakistan.

Faculty of Pharmacy and Biomedical Sciences, Mahsa University, Jenjarom, Selangor, Malaysia.

出版信息

Int J Gen Med. 2025 Aug 27;18:4763-4783. doi: 10.2147/IJGM.S519184. eCollection 2025.

Abstract

BACKGROUND AND AIM

A major global public health concern is hypertension, particularly in low- and middle-income countries like Pakistan. Despite the fact that its physical manifestations are widely recognized, little is known about its psychological effects and how they impact patients' quality of life (QoL) in clinical practice and research. The current study examined the relationship between the quality of life of patients with hypertension and psychological distress, including stress, anxiety, and depression.

METHODS

A total of 385 patients were recruited from a tertiary care facility in Lahore using a cross-sectional approach. The Depression, Anxiety, and Stress Scale (DASS-21) was used to measure psychological distress, and the 12-item Short Form Health Survey (SF-12) was used to measure quality of life. The Physical Component Summary (PCS-12) and the Mental Component Summary (MCS-12) are the two summary scores that are produced by the SF-12. Non-parametric tests like the Kruskal-Wallis -test and the Mann-Whitney -test were used in the statistical analysis.

RESULTS

The findings showed substantial levels of psychological discomfort, with the most common severities being very severe anxiety (50.1%), severe depression (31.2%), and severe stress (46.8%). More significantly, there was a high association (p<0.001) between lower PCS-12 and MCS-12 scores and depression, anxiety, and stress, indicating a substantial negative impact of psychological distress on both the mental and physical aspects of quality of life. Psychological health and QoL results were also predicted by sociodemographic characteristics, including age, gender, income, education, and work status.

CONCLUSION

These findings highlight the value of integrating psychological evaluation and psychiatric assistance into the management of hypertension for enhanced overall health outcomes as well as patient quality of life.

摘要

背景与目的

高血压是一个重大的全球公共卫生问题,在巴基斯坦等低收入和中等收入国家尤为突出。尽管其身体表现已广为人知,但在临床实践和研究中,人们对其心理影响以及这些影响如何影响患者的生活质量(QoL)却知之甚少。本研究探讨了高血压患者的生活质量与心理困扰(包括压力、焦虑和抑郁)之间的关系。

方法

采用横断面研究方法,从拉合尔的一家三级医疗保健机构招募了385名患者。使用抑郁、焦虑和压力量表(DASS-21)测量心理困扰,使用12项简短健康调查问卷(SF-12)测量生活质量。SF-12产生两个总结分数,即身体成分总结(PCS-12)和心理成分总结(MCS-12)。统计分析采用非参数检验,如Kruskal-Wallis检验和Mann-Whitney检验。

结果

研究结果显示心理不适程度较高,最常见的严重程度为非常严重的焦虑(50.1%)、严重抑郁(31.2%)和严重压力(46.8%)。更重要的是,PCS-12和MCS-12得分较低与抑郁、焦虑和压力之间存在高度关联(p<0.001),表明心理困扰对生活质量的心理和身体方面都有重大负面影响。社会人口学特征,包括年龄、性别、收入、教育程度和工作状态,也可预测心理健康和生活质量结果。

结论

这些发现强调了将心理评估和精神科援助纳入高血压管理的价值,以改善整体健康结果和患者生活质量。

相似文献

4
Investigation and analysis of mental health status of the older adult in western rural areas.
Front Public Health. 2025 Jul 16;13:1612600. doi: 10.3389/fpubh.2025.1612600. eCollection 2025.
5
Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review.
Cochrane Database Syst Rev. 2018 Apr 17;4(4):CD010842. doi: 10.1002/14651858.CD010842.pub2.
6
The Black Book of Psychotropic Dosing and Monitoring.
Psychopharmacol Bull. 2024 Jul 8;54(3):8-59.
7
Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases.
Cochrane Database Syst Rev. 2024 Sep 12;9(9):CD015383. doi: 10.1002/14651858.CD015383.pub2.
8
Psychological therapies for the treatment of mental disorders in low- and middle-income countries affected by humanitarian crises.
Cochrane Database Syst Rev. 2018 Jul 5;7(7):CD011849. doi: 10.1002/14651858.CD011849.pub2.
9
Factors that influence participation in physical activity for people with bipolar disorder: a synthesis of qualitative evidence.
Cochrane Database Syst Rev. 2024 Jun 4;6(6):CD013557. doi: 10.1002/14651858.CD013557.pub2.
10
Psychosocial interventions for men with prostate cancer.
Cochrane Database Syst Rev. 2013 Dec 24;2013(12):CD008529. doi: 10.1002/14651858.CD008529.pub3.

本文引用的文献

1
Psychological stress among hypertensive male patients in Jordan: prevalence and associated factors.
BMC Public Health. 2024 Dec 18;24(1):3508. doi: 10.1186/s12889-024-20733-0.
2
Prevalence of depression in hypertensive patients and its associated factors in India: A systematic review and meta-analysis.
Hipertens Riesgo Vasc. 2024 Oct-Dec;41(4):217-225. doi: 10.1016/j.hipert.2024.05.003. Epub 2024 Jul 2.
5
Latent profile analysis of depression in non-hospitalized elderly patients with hypertension and its influencing factors.
J Affect Disord. 2023 Nov 15;341:67-76. doi: 10.1016/j.jad.2023.08.114. Epub 2023 Aug 24.
7
Anxiety disorders and depression are associated with resistant hypertension.
Adv Clin Exp Med. 2024 Feb;33(2):111-118. doi: 10.17219/acem/166304.
8
Challenges of managing hypertension in Pakistan - a review.
Clin Hypertens. 2023 Jun 15;29(1):17. doi: 10.1186/s40885-023-00245-6.
9
Comorbidity of Anxiety and Hypertension: Common Risk Factors and Potential Mechanisms.
Int J Hypertens. 2023 May 25;2023:9619388. doi: 10.1155/2023/9619388. eCollection 2023.
10
Impacts of Anxiety and Depression on Clinical Hypertension in Low-Income US Adults.
High Blood Press Cardiovasc Prev. 2023 Jul;30(4):337-342. doi: 10.1007/s40292-023-00584-3. Epub 2023 Jun 1.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验