Fatima Maham, Aslam Adeel, Ijaz Maheen, Anwar Mudassir, Jamshed Shazia, Asiri Saeed, Syed Wajid
Faculty of Pharmacy, University of Lahore, Lahore, Pakistan.
Faculty of Pharmacy and Biomedical Sciences, Mahsa University, Jenjarom, Selangor, Malaysia.
Int J Gen Med. 2025 Aug 27;18:4763-4783. doi: 10.2147/IJGM.S519184. eCollection 2025.
A major global public health concern is hypertension, particularly in low- and middle-income countries like Pakistan. Despite the fact that its physical manifestations are widely recognized, little is known about its psychological effects and how they impact patients' quality of life (QoL) in clinical practice and research. The current study examined the relationship between the quality of life of patients with hypertension and psychological distress, including stress, anxiety, and depression.
A total of 385 patients were recruited from a tertiary care facility in Lahore using a cross-sectional approach. The Depression, Anxiety, and Stress Scale (DASS-21) was used to measure psychological distress, and the 12-item Short Form Health Survey (SF-12) was used to measure quality of life. The Physical Component Summary (PCS-12) and the Mental Component Summary (MCS-12) are the two summary scores that are produced by the SF-12. Non-parametric tests like the Kruskal-Wallis -test and the Mann-Whitney -test were used in the statistical analysis.
The findings showed substantial levels of psychological discomfort, with the most common severities being very severe anxiety (50.1%), severe depression (31.2%), and severe stress (46.8%). More significantly, there was a high association (p<0.001) between lower PCS-12 and MCS-12 scores and depression, anxiety, and stress, indicating a substantial negative impact of psychological distress on both the mental and physical aspects of quality of life. Psychological health and QoL results were also predicted by sociodemographic characteristics, including age, gender, income, education, and work status.
These findings highlight the value of integrating psychological evaluation and psychiatric assistance into the management of hypertension for enhanced overall health outcomes as well as patient quality of life.
高血压是一个重大的全球公共卫生问题,在巴基斯坦等低收入和中等收入国家尤为突出。尽管其身体表现已广为人知,但在临床实践和研究中,人们对其心理影响以及这些影响如何影响患者的生活质量(QoL)却知之甚少。本研究探讨了高血压患者的生活质量与心理困扰(包括压力、焦虑和抑郁)之间的关系。
采用横断面研究方法,从拉合尔的一家三级医疗保健机构招募了385名患者。使用抑郁、焦虑和压力量表(DASS-21)测量心理困扰,使用12项简短健康调查问卷(SF-12)测量生活质量。SF-12产生两个总结分数,即身体成分总结(PCS-12)和心理成分总结(MCS-12)。统计分析采用非参数检验,如Kruskal-Wallis检验和Mann-Whitney检验。
研究结果显示心理不适程度较高,最常见的严重程度为非常严重的焦虑(50.1%)、严重抑郁(31.2%)和严重压力(46.8%)。更重要的是,PCS-12和MCS-12得分较低与抑郁、焦虑和压力之间存在高度关联(p<0.001),表明心理困扰对生活质量的心理和身体方面都有重大负面影响。社会人口学特征,包括年龄、性别、收入、教育程度和工作状态,也可预测心理健康和生活质量结果。
这些发现强调了将心理评估和精神科援助纳入高血压管理的价值,以改善整体健康结果和患者生活质量。