Faymonville M E, Fissette J, Mambourg P H, Roediger L, Joris J, Lamy M
Department of Anesthesia and Intensive Care Medicine, University of Liège, Belgium.
Reg Anesth. 1995 Mar-Apr;20(2):145-51.
Sedation is often requested during local and regional anesthesia. However, some surgical procedures, such as plastic surgery, require conscious sedation, which may be difficult to achieve. Hypnosis, used routinely to provide conscious sedation in the authors' Department of Plastic Surgery, results in high patient and surgeon satisfaction. The authors conducted a retrospective study to investigate the benefits of hypnosis in supplementing local anesthesia.
The study included 337 patients undergoing minor and major plastic surgical procedures under local anesthesia and conscious intravenous sedation. Patients were divided into three groups depending on the sedation technique: intravenous sedation (n = 137) using only midazolam and alfentanil; hypnosis (n = 172), during which patients achieved a hypnotic trance level with age regression; and relaxation (n = 28), comprising patients in whom hypnosis was induced without attaining a trance level. In all three groups, midazolam and alfentanil were titrated to achieve patient immobility, in response to patient complaints, and to maintain hemodynamic stability. Midazolam and alfentanil requirements; intra- and postoperative pain scores; as well as pre-, intra-, and postoperative anxiety score, reported on a 10-cm visual analog scale, were recorded and compared in the three groups.
Intraoperative anxiety reported by patients in the hypnosis group (0.7 +/- 0.11) and in the relaxation group (2.08 +/- 0.4) was significantly (P < .001) less than in the intravenous sedation group (5.6 +/- 1.6). Pain scores during surgery were significantly greater in the intravenous sedation group (4.9 +/- 0.6) than in the hypnosis group (1.36 +/- 0.12; P < .001) and the relaxation group (1.82 +/- 0.6; P < .01). Furthermore, midazolam requirements were significantly lower in the hypnosis group (P < .001) and in the relaxation group (P < .01) as compared with the intravenous sedation group: respectively, 0.04 +/- 0.002, 0.07 +/- 0.005, and 0.11 +/- 0.01 mg/kg/h. Alfentanil requirements were significantly decreased in the hypnosis group, as compared with the intravenous sedation group: 10.2 +/- 0.6 microgram/kg/h versus 15.5 +/- 2.07 micrograms/kg/h; P < .002. In the relaxation group, alfentanil requirements were 14.3 +/- 1.5 micrograms/kg/h (ns). Postoperative nausea and vomiting were reported by 1.2% of patients in the hypnosis group, 12.8% in the relaxation group and 26.7% in the intravenous sedation group. Greater patient satisfaction with the anesthetic procedure and greater surgical comfort were also reported in the hypnosis group.
Successful hypnosis as an adjunct sedation procedure to conscious intravenous sedation provided better pain and anxiety relief than conventional intravenous sedation and allowed for a significant reduction in midazolam and alfentanil requirements. Patient satisfaction was significantly improved.
在局部和区域麻醉过程中,常常需要进行镇静。然而,一些外科手术,如整形手术,需要清醒镇静,这可能难以实现。在作者所在的整形科,常规使用催眠术来提供清醒镇静,患者和外科医生的满意度都很高。作者进行了一项回顾性研究,以调查催眠术在补充局部麻醉方面的益处。
该研究纳入了337例在局部麻醉和清醒静脉镇静下接受小型和大型整形手术的患者。根据镇静技术将患者分为三组:仅使用咪达唑仑和阿芬太尼的静脉镇静组(n = 137);催眠组(n = 172),在此过程中患者通过年龄回溯达到催眠恍惚状态;放松组(n = 28),包括那些诱导了催眠但未达到恍惚状态的患者。在所有三组中,根据患者的主诉滴定咪达唑仑和阿芬太尼,以实现患者不动,并维持血流动力学稳定。记录并比较三组患者的咪达唑仑和阿芬太尼需求量;术中和术后疼痛评分;以及术前、术中和术后焦虑评分(采用10厘米视觉模拟量表)。
催眠组(0.7±0.11)和放松组(2.08±0.4)患者报告的术中焦虑显著低于静脉镇静组(5.6±1.6)(P <.001)。静脉镇静组手术期间的疼痛评分(4.9±0.6)显著高于催眠组(1.36±0.12;P <.001)和放松组(1.82±0.6;P <.01)。此外,与静脉镇静组相比,催眠组(P <.001)和放松组(P <.01)的咪达唑仑需求量显著更低:分别为0.04±0.002、0.07±0.005和0.11±0.01 mg/kg/h。与静脉镇静组相比,催眠组的阿芬太尼需求量显著降低:10.2±0.6微克/千克/小时对15.5±2.07微克/千克/小时;P <.002。在放松组中,阿芬太尼需求量为14.3±1.5微克/千克/小时(无显著差异)。催眠组1.2%的患者报告有术后恶心和呕吐,放松组为12.8%,静脉镇静组为26.7%。催眠组患者对麻醉过程的满意度更高,手术舒适度也更高。
成功的催眠术作为清醒静脉镇静的辅助镇静程序,比传统静脉镇静能更好地缓解疼痛和焦虑,并能显著降低咪达唑仑和阿芬太尼的需求量。患者满意度显著提高。