[背侧海马体在褪黑素和地西泮抗焦虑作用中的参与]
[The participation of the dorsal hippocampus in the antianxiety action of melatonin and diazepam].
作者信息
Arushanian E B, Beĭer E V
机构信息
Department of Pharmacology, Stavropol Medical Academy, Russia.
出版信息
Eksp Klin Farmakol. 1998 Mar-Apr;61(2):13-6.
PMID:9621165
Abstract
The pineal hormone melatonin and the tranquilizer diazepam given in an equal dose (0.1 mg/kg) demonstrated an anxiolytic effect on a model of a conflict situation in rats. Damage to the dorsal hippocampus produced a similar effect and the anxiolytic activity of the drugs under study was removed against this background.
摘要
给予大鼠同等剂量（0.1毫克/千克）的松果体激素褪黑素和镇静剂地西泮，在冲突情境模型中显示出抗焦虑作用。损毁背侧海马体产生了类似的效果，并且在这种背景下，所研究药物的抗焦虑活性消失。
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