Kanter R J, Papagiannis J, Carboni M P, Ungerleider R M, Sanders W E, Wharton J M
Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.
J Am Coll Cardiol. 2000 Feb;35(2):428-41. doi: 10.1016/s0735-1097(99)00557-4.
The purpose of this study was to determine the efficacy and risks of radiofrequency ablation of various forms of supraventricular tachycardia after Mustard and Senning operations for d-transposition of the great arteries.
In this patient group, the reported success rate of catheter ablation of intraatrial reentry tachycardia is about 70% with a negligible complication rate. There are no reports of the use of radiofrequency ablation to treat other types of supraventricular tachycardia.
Standard diagnostic criteria were used to determine supraventricular tachycardia type. Appropriate sites for attempted ablation included 1) intraatrial reentry tachycardia: presence of concealed entrainment with a postpacing interval similar to tachycardia cycle length; 2) focal atrial tachycardia: a P-A interval < or =-20 ms; and 3) typical variety of atrioventricular (AV) node reentry tachycardia: combined electrographic and radiographic features.
Nine Mustard and two Senning patients underwent 13 studies to successfully ablate all supraventricular tachycardia substrates in eight (73%) patients. Eight of eleven (73%) patients having intraatrial reentry tachycardia, 3/3 having typical AV node reentry tachycardia, and 2/2 having focal atrial reentry tachycardia were successfully ablated. Among five patients having intraatrial reentry tachycardia (IART) and not having ventriculoatrial (V-A) conduction, two suffered high-grade AV block when ablation of the systemic venous portion of the medial tricuspid valve/inferior vena cava isthmus was attempted.
Radiofrequency catheter ablation can be effectively and safely performed for certain supraventricular tachycardia types in addition to intraatrial reentry. A novel catheter course is required for slow pathway modification. High-grade AV block is a potential risk of lesions placed in the systemic venous medial isthmus.
本研究旨在确定在Mustard和Senning手术治疗大动脉d型转位后,射频消融各种形式室上性心动过速的疗效和风险。
在该患者群体中,据报道心房内折返性心动过速导管消融的成功率约为70%,并发症发生率可忽略不计。尚无使用射频消融治疗其他类型室上性心动过速的报道。
采用标准诊断标准确定室上性心动过速类型。尝试消融的合适部位包括:1)心房内折返性心动过速:存在隐匿性拖带,起搏后间期与心动过速周期长度相似;2)局灶性房性心动过速:P - A间期≤ - 20 ms;3)典型的房室结折返性心动过速:结合心电图和影像学特征。
9例Mustard手术患者和2例Senning手术患者接受了13次研究,成功消融了8例(73%)患者的所有室上性心动过速基质。11例(73%)心房内折返性心动过速患者中的8例、3例典型房室结折返性心动过速患者中的3例以及2例局灶性房性折返性心动过速患者中的2例均成功消融。在5例有心房内折返性心动过速(IART)且无室房(V - A)传导的患者中,尝试消融三尖瓣内侧/下腔静脉峡部的体静脉部分时,2例发生了高度房室传导阻滞。
除心房内折返外,射频导管消融对某些类型的室上性心动过速可有效且安全地进行。改良慢径需要一种新的导管路径。高度房室传导阻滞是在体静脉内侧峡部进行消融的潜在风险。