Pisano E D, Cole E B, Major S, Zong S, Hemminger B M, Muller K E, Johnston R E, Walsh R, Conant E, Fajardo L L, Feig S A, Nishikawa R M, Yaffe M J, Williams M B, Aylward S R
Dept of Radiology, University of North Carolina CB7510, Chapel Hill, NC 27599-7510, USA.
Radiology. 2000 Sep;216(3):820-30. doi: 10.1148/radiology.216.3.r00se48820.
To determine the preferences of radiologists among eight different image processing algorithms applied to digital mammograms obtained for screening and diagnostic imaging tasks.
Twenty-eight images representing histologically proved masses or calcifications were obtained by using three clinically available digital mammographic units. Images were processed and printed on film by using manual intensity windowing, histogram-based intensity windowing, mixture model intensity windowing, peripheral equalization, multiscale image contrast amplification (MUSICA), contrast-limited adaptive histogram equalization, Trex processing, and unsharp masking. Twelve radiologists compared the processed digital images with screen-film mammograms obtained in the same patient for breast cancer screening and breast lesion diagnosis.
For the screening task, screen-film mammograms were preferred to all digital presentations, but the acceptability of images processed with Trex and MUSICA algorithms were not significantly different. All printed digital images were preferred to screen-film radiographs in the diagnosis of masses; mammograms processed with unsharp masking were significantly preferred. For the diagnosis of calcifications, no processed digital mammogram was preferred to screen-film mammograms.
When digital mammograms were preferred to screen-film mammograms, radiologists selected different digital processing algorithms for each of three mammographic reading tasks and for different lesion types. Soft-copy display will eventually allow radiologists to select among these options more easily.
确定放射科医生对于应用于乳腺筛查和诊断成像任务的八 种不同图像处理算法的偏好。
使用三台临床可用的数字乳腺摄影设备获取了代表经组织学证实的肿块或钙化的28幅图像。通过手动强度窗技术、基于直方图的强度窗技术、混合模型强度窗技术、周边均衡化、多尺度图像对比度增强(MUSICA)、对比度受限自适应直方图均衡化、Trex处理和锐化掩膜处理对图像进行处理并打印在胶片上。12名放射科医生将处理后的数字图像与同一患者用于乳腺癌筛查和乳腺病变诊断的屏-片乳腺造影片进行比较。
对于筛查任务,屏-片乳腺造影片比所有数字图像更受青睐,但经Trex和MUSICA算法处理的图像的可接受性没有显著差异。在肿块诊断中,所有打印的数字图像比屏-片X线片更受青睐;经锐化掩膜处理的乳腺造影片明显更受青睐。对于钙化的诊断,没有处理后的数字乳腺造影片比屏-片乳腺造影片更受青睐。
当数字乳腺造影片比屏-片乳腺造影片更受青睐时,放射科医生针对三种乳腺X线阅读任务中的每一项以及不同的病变类型选择了不同的数字处理算法。软拷贝显示最终将使放射科医生能够更轻松地在这些选项中进行选择。