GAL4基因剂量对酿酒酵母中半乳糖分解代谢酶水平的影响。
Effect of GAL4 gene dosage on the level of galactose catabolic enzymes in Saccharomyces cerevisiae.
作者信息
Klar A J, Halvorson H O
出版信息
J Bacteriol. 1976 Jan;125(1):379-81. doi: 10.1128/jb.125.1.379-381.1976.
Abstract
Lack of GAL4 gene dosage on the level of uridine diphosphogalactose epimerase (EC 5.1.3.2) activity suggests the positive regulatory role for this locus on the control of galactose catabolic enzymes in Saccharomyces cerevisiae.
摘要
在尿苷二磷酸半乳糖表异构酶（EC 5.1.3.2）活性水平上缺乏GAL4基因剂量，表明该基因座对酿酒酵母中半乳糖分解代谢酶的控制具有正向调节作用。
相似文献
1
Effect of GAL4 gene dosage on the level of galactose catabolic enzymes in Saccharomyces cerevisiae.
J Bacteriol. 1976 Jan;125(1):379-81. doi: 10.1128/jb.125.1.379-381.1976.
2
The enzymes of the galactose cluster in Saccharomyces cerevisiae. II. Purification and characterization of uridine diphosphoglucose 4-epimerase.
J Biol Chem. 1980 Apr 10;255(7):2705-7.
3
Characterization of the Saccharomyces cerevisiae galactose mutarotase/UDP-galactose 4-epimerase protein, Gal10p.
FEMS Yeast Res. 2007 May;7(3):366-71. doi: 10.1111/j.1567-1364.2006.00204.x. Epub 2007 Jan 24.
4
Mechanism of inactivation of UDP-glucose 4-epimerase from Saccharomyces cerevisiae by D-xylose and L-arabinose.
Yeast. 1986 Jun;2(2):101-8. doi: 10.1002/yea.320020205.
5
UDPGlucose 4-epimerase from Saccharomyces fragilis. Allosteric kinetics with UDP-glucose as substrate.
J Biol Chem. 1975 Jun 10;250(11):4373-5.
6
The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae.
J Biol Chem. 2005 Jun 10;280(23):21900-7. doi: 10.1074/jbc.M502411200. Epub 2005 Mar 28.
7
UDPglucose 4-epimerase from Saccharomyces fragilis: asymmetry in allosteric properties leads to unidirectional catalysis.
Biochem Biophys Res Commun. 1978 Nov 14;85(1):242-8. doi: 10.1016/s0006-291x(78)80035-7.
8
UDPgalactose 4-epimerase from Saccharomyces cerevisiae. A bifunctional enzyme with aldose 1-epimerase activity.
Eur J Biochem. 2004 Feb;271(4):753-9. doi: 10.1111/j.1432-1033.2003.03974.x.
9
Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae. II. The isolation and dosage effect of the regulatory gene GAL80.
Mol Gen Genet. 1984;195(1-2):29-34. doi: 10.1007/BF00332719.
10
Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesizing galactose-metabolizing enzymes.
Mol Cell Biol. 1984 May;4(5):994-6. doi: 10.1128/mcb.4.5.994-996.1984.
引用本文的文献
1
Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein.
J Bacteriol. 1980 Feb;141(2):508-27. doi: 10.1128/jb.141.2.508-527.1980.
2
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.
Proc Natl Acad Sci U S A. 1982 Nov;79(22):6971-5. doi: 10.1073/pnas.79.22.6971.
3
Acid phosphatase polypeptides in Saccharomyces cerevisiae are encoded by a differentially regulated multigene family.
Proc Natl Acad Sci U S A. 1982 Apr;79(7):2157-61. doi: 10.1073/pnas.79.7.2157.
4
Genetic and biochemical identification of the glutamate synthase structural gene in Neurospora crassa.
J Bacteriol. 1986 Sep;167(3):1043-7. doi: 10.1128/jb.167.3.1043-1047.1986.
5
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae.
Microbiol Rev. 1987 Dec;51(4):458-76. doi: 10.1128/mr.51.4.458-476.1987.
6
Gene dosage effects on the synthesis of maltase in yeast.
J Bacteriol. 1979 Mar;137(3):1200-7. doi: 10.1128/jb.137.3.1200-1207.1979.
7
Interaction of super-repressible and dominant constitutive mutations for the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae.
Mol Gen Genet. 1977 Apr 29;152(3):137-44. doi: 10.1007/BF00268810.
8
Genetic control of galactokinase synthesis in Saccharomyces cerevisiae: evidence for constitutive expression of the positive regulatory gene gal4.
J Bacteriol. 1978 May;134(2):446-57. doi: 10.1128/jb.134.2.446-457.1978.
本文引用的文献
1
GENE DOSAGE AND GALACTOSE UTILIZATION BY SACCHAROMYCES TETRAPLOIDS.
Genetics. 1963 Dec;48(12):1585-91. doi: 10.1093/genetics/48.12.1585.
2
COMPLEMENTATION STUDIES OF ARABINOSE GENES IN ESCHERICHIA COLI.
Genetics. 1963 Oct;48(10):1397-410. doi: 10.1093/genetics/48.10.1397.
3
The genetic basis of hyper-synthesis of beta-galactosidase.
Genetics. 1963 Feb;48(2):157-69. doi: 10.1093/genetics/48.2.157.
4
Regulation of genes controlling synthesis of the galactose pathway enzymes in yeast.
Genetics. 1966 Sep;54(3):911-6. doi: 10.1093/genetics/54.3.911.
5
Genetic regulation of xanthine dehydrogenase in Drosophila melanogaster.
Fed Proc. 1965 Sep-Oct;24(5):1243-51.
6
Biochemical genetics of yeast.
Annu Rev Genet. 1970;4:373-96. doi: 10.1146/annurev.ge.04.120170.002105.
7
Studies on the positive regulatory gene, GAL4, in regulation of galactose catabolic enzymes in Saccharomyces cerevisiae.
Mol Gen Genet. 1974;135(3):203-12. doi: 10.1007/BF00268616.
8
Regulation: positive control.
Annu Rev Genet. 1974;8:219-42. doi: 10.1146/annurev.ge.08.120174.001251.
9
Dilution kinetic studies of yeast populations: in vivo aggregation of galactose utilizing enzymes and positive regulator molecules.
Genetics. 1974 Jul;77(3):491-505. doi: 10.1093/genetics/77.3.491.
Zotero 插件