Hanifin J M, Thurston M, Omoto M, Cherill R, Tofte S J, Graeber M
Department of Dermatology, Oregon Health Sciences University, Portland 97201-3098, USA.
Exp Dermatol. 2001 Feb;10(1):11-8. doi: 10.1034/j.1600-0625.2001.100102.x.
To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency.
Training of evaluators, application, and assessment over 2 consecutive days.
An academic center.
Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients > or = 8 years) and cohort 2 (10 patients < 8 years).
None.
The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed.
Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days.
This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.
通过评估观察者间和观察者内的一致性,测试湿疹面积和严重程度指数(EASI)评分系统的可靠性。
对评估者进行培训,连续两天进行应用和评估。
一个学术中心。
20名患有特应性皮炎(AD)的成人和儿童;队列1(10名年龄≥8岁的患者)和队列2(10名年龄<8岁的患者)。
无。
15名皮肤科评估者连续两天使用EASI对队列1和队列2中的特应性皮炎进行评估。分析观察者间和观察者内的可靠性。
EASI的总体评估者内可靠性处于中等至良好范围。评估者间可靠性分析表明,评估者在两个研究日对患者的评估具有一致性。
本研究表明,EASI可以快速掌握并可靠地用于评估AD的严重程度和范围。评估者在连续两天的评估之间具有一致性。这些结果支持在AD治疗药物的临床试验中使用EASI。