Kimura T, Adachi M
First Department of Internal Medicine, School of Medicine, Showa University.
Nihon Rinsho. 2001 Oct;59(10):1992-9.
Several classes of medications are used in the treatment of bronchial asthma. Inhaled corticosteroids are the most potent and effective anti-inflammatory agents. The addition of a long-acting beta 2-adrenergic bronchodilator to inhaled corticosteroids for the treatment of asthma has been shown to improve pulmonary function. Combining an inhaled corticosteroid, fluticasone propionate with a long-acting beta 2-adrenergic bronchodilator, salmeterol in a single inhaler permits treatment of both the inflammatory and bronchoconstrictive components of asthma. Combination treatment with fluticasone and salmeterol improves symptoms and lung function, reduces supplemental use of short-acting beta 2-adrenergic bronchodilator. The combination therapy provides better asthma control and may simplify the management of asthma.
有几类药物用于治疗支气管哮喘。吸入性糖皮质激素是最有效且最具效力的抗炎药物。已证实,在吸入性糖皮质激素中添加长效β2肾上腺素能支气管扩张剂用于治疗哮喘可改善肺功能。将吸入性糖皮质激素丙酸氟替卡松与长效β2肾上腺素能支气管扩张剂沙美特罗联合在一个吸入器中,可同时治疗哮喘的炎症和支气管收缩成分。丙酸氟替卡松和沙美特罗联合治疗可改善症状和肺功能,减少短效β2肾上腺素能支气管扩张剂的补充使用。联合治疗能更好地控制哮喘,且可能简化哮喘的管理。