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糖尿病患者行白内障囊外摘除联合后房型人工晶状体植入术——145例患者的回顾性研究

[Extracapsular cataract surgery with posterior chamber lens implantation in patients with diabetes mellitus - retrospective study on 145 patients].

作者信息

Kutschan Annette, Heinz Peter, Wiegand Wolfgang

机构信息

Augenabteilung Klinikum Nord/Heidelberg, Tangstedter Landstrasse 400, 22413 Hamburg, Germany.

出版信息

Klin Monbl Augenheilkd. 2002 Mar;219(3):117-24. doi: 10.1055/s-2002-26720.

Abstract

BACKGROUND

The purpose of this paper is to investigate whether cataract surgery in patients with diabetes mellitus influences the progression of diabetic retinopathy, diabetic macular oedema and anterior segment complications.

PATIENTS AND METHODS

145 consecutive patients with type-II-diabetes mellitus underwent an extracapsular cataract surgery with implantation of a posterior chamber lens. 88 patients (119 eyes have been operated) could be followed up for an average of 19 months and 58 patients (88 eyes have been operated) could be followed up for an average of 38 months. Evaluation of the data included the preoperative retinal findings, intraoperative and early postoperative complications and problems, the progression of diabetic fundus changes, the progression of visual acuity and late complications.

RESULTS

Insufficient pupil dilatation (25.2 %) was the most frequent intraoperative complication. Among early postoperative complications anterior segment inflammation was most frequent (10.1 %). During the follow-up period the diabetic retinopathy in the operated eyes showed a progression which was statistically not different from that in the non-operated eyes. After an average of 19 months the diabetic retinopathy deteriorated in 22.7 % of the operated eyes and in 17.5 % of the non-operated eyes. After an average of 38 months the diabetic retinopathy deteriorated in additional 12.5 % of the operated and 11.1 % of the not-operated eyes. A diabetic macular oedema was present after an average of 19 months in 6.8 % of the operated 119 eyes and after an average of 38 months in 6.7 % of the operated 88 eyes. In the non-operated partner-eyes no diabetic macular edema developed during the follow-up period. The main late-complication during the whole follow-up period was the development of a capsular fibrosis in 52.3 % of the operated eyes. Postoperative visual acuity at the end of the first follow-up period (average 19 months) was >/= 0.5 in 85.7 % of the operated eyes and at the end of the second follow-up period (average 38 months) in 81.8 % of the operated eyes.

CONCLUSION

Extracapsular cataract surgery in patients with diabetes mellitus is a procedure with good results, of high reliability and a slightly higher rate of complications than in non-diabetic patients. Extracapsular cataract surgery does not give rise to progression of diabetic retinopathy.

摘要

背景

本文旨在研究糖尿病患者的白内障手术是否会影响糖尿病视网膜病变、糖尿病性黄斑水肿及眼前段并发症的进展。

患者与方法

145例连续的II型糖尿病患者接受了囊外白内障摘除术并植入后房型人工晶状体。88例患者(119只眼接受了手术)平均随访19个月,58例患者(88只眼接受了手术)平均随访38个月。数据评估包括术前视网膜检查结果、术中及术后早期并发症和问题、糖尿病眼底改变的进展、视力进展及晚期并发症。

结果

瞳孔散大不足(25.2%)是最常见的术中并发症。术后早期并发症中,眼前段炎症最为常见(10.1%)。在随访期间,手术眼的糖尿病视网膜病变进展情况与未手术眼相比,在统计学上无差异。平均19个月后,手术眼糖尿病视网膜病变恶化的比例为22.7%,未手术眼为17.5%。平均38个月后,手术眼糖尿病视网膜病变又有12.5%恶化,未手术眼为11.1%。平均19个月后,119只接受手术的眼中有6.8%出现糖尿病性黄斑水肿,平均38个月后,88只接受手术的眼中有6.7%出现该情况。在随访期间,未手术的对侧眼中未出现糖尿病性黄斑水肿。整个随访期间的主要晚期并发症是5所接受手术的眼中有52.3%发生了囊膜纤维化。第一次随访期末(平均19个月),85.7%的手术眼术后视力≥0.5,第二次随访期末(平均38个月),81.8%的手术眼达到该视力。

结论

糖尿病患者的囊外白内障手术效果良好,可靠性高,并发症发生率略高于非糖尿病患者。囊外白内障手术不会导致糖尿病视网膜病变进展。

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