羟基取代的寡聚吡啶二羧酰胺螺旋折叠体
Hydroxy-substituted oligopyridine dicarboxamide helical foldamers.
作者信息
Huc Ivan, Maurizot Victor, Gornitzka Heinz, Léger Jean-Michel
机构信息
Institut Européen de Chimie et Biologie, 16 av. Pey Berland, 33607 Pessac, France.
出版信息
Chem Commun (Camb). 2002 Mar 21(6):578-9. doi: 10.1039/b111612f.
DOI:10.1039/b111612f
PMID:12120131
Abstract
As shown by X-ray diffraction and NMR studies, short oligopyridine dicarboxamides bearing benzyloxy, hydroxy and hydroxylate moieties adopt very robust single helical conformations, even in water.
摘要
如X射线衍射和核磁共振研究所示，带有苄氧基、羟基和羟基化物部分的短寡聚吡啶二羧酸酰胺即使在水中也能呈现非常稳定的单螺旋构象。
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