Wang Yinsong, Tan Mingguang, Huang Zongzhi, Sheng Liqin, Ge Yongxin, Zhang Hongde, Jiang Mingli, Zhang Guilin
Shanghai Institute of Nuclear Research, China.
Biol Trace Elem Res. 2002 Aug;88(2):113-8. doi: 10.1385/BTER:88:2:113.
Diabetes mellitus is characterized by hyperglycemia and is closely related to trace elements. Quite a few pregnant women suffer from impaired glucose tolerance (IGT) or gestational diabetes mellitus (GDM). Investigation of the changes of elemental contents in serum of the pregnant women with IGT and GDM is significant in the etiological research and cure of the diseases. In the present work, the elements Cu, Zn, Ca, Sr, Mg, P, Fe, and Al in the serum of pregnant women were determined. The elemental contents in different experimental groups were compared. Also, the correlation between elemental contents and gestational period was observed. The results showed that compared with normal pregnant women, the Cu contents in serum of pregnant women with GDM increased, but Zn contents had a decreasing trend. In addition, for all pregnant women, the Ca contents in serum had an obvious inverse correlation with gestational period.
糖尿病以高血糖为特征,且与微量元素密切相关。相当多的孕妇患有糖耐量受损(IGT)或妊娠期糖尿病(GDM)。对患有IGT和GDM的孕妇血清中元素含量变化的研究,在这些疾病的病因研究和治疗中具有重要意义。在本研究中,测定了孕妇血清中的铜(Cu)、锌(Zn)、钙(Ca)、锶(Sr)、镁(Mg)、磷(P)、铁(Fe)和铝(Al)元素。比较了不同实验组中的元素含量。此外,还观察了元素含量与妊娠期之间的相关性。结果表明,与正常孕妇相比,患有GDM的孕妇血清中的铜含量增加,但锌含量呈下降趋势。此外,对于所有孕妇,血清中的钙含量与妊娠期呈明显的负相关。