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Interleukin-15 and the regulation of lymphoid homeostasis.

作者信息

Lodolce James, Burkett Patrick, Koka Rima, Boone David, Chien Marcia, Chan Faye, Madonia Michelle, Chai Sophia, Ma Averil

机构信息

Department of Medicine and the Ben May Institute for Cancer Research, University of Chicago, 5841 S. Maryland Avenue MC 6084, Chicago, IL 60637, USA.

出版信息

Mol Immunol. 2002 Dec;39(9):537-44. doi: 10.1016/s0161-5890(02)00211-0.

Abstract

Interleukin-15 (IL-15) is a cytokine that plays unique roles in both innate and adaptive immune cell homeostasis. While early studies suggested that IL-15 resembled IL-2, more recent work suggests that IL-15 may play multiple unique roles in immune homeostasis befitting its pleiotropic expression pattern. This review will focus on recent studies that highlight some of these functions.

摘要

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