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霍香抗菌活性的评估

Evaluation of antimicrobial activities of Satureja hortensis L.

作者信息

Sahin F, Karaman I, Güllüce M, Oğütçü H, Sengül M, Adigüzel A, Oztürk S, Kotan R

机构信息

Department of Plant Protection, Faculty of Agriculture, Ataturk University, Erzurum 25240, Turkey.

出版信息

J Ethnopharmacol. 2003 Jul;87(1):61-5. doi: 10.1016/s0378-8741(03)00110-7.

Abstract

The present study was designated to evaluate the antimicrobial activities of methonol and hexane extracts of Satureja hortensis L. which is an annual herb used as traditional folk medicine in Eastern Anatolia region of Turkey for the treatment of different infectious diseases and disorders. The antimicrobial activities of the extracts against 147 laboratory strains belong to 55 bacterial species, and 31 isolates of 1 yeast and 4 fungi species were tested by using disc diffusion assay. The results showed that hexane extract of Satureja hortensis had no antifungal, but antibacterial activity against four strains of three Bacillus species whereas methanol extract of Satureja hortensis had both anticandidal and antibacterial effects. It inhibited the growth of 23 strains of 11 bacterial species and 6 isolates of Candida albicans, at the concentration of 300microg/ml. Satureja hortensis did not show antimicrobial activity against the remaining microorganisms (83%) tested including most and all of the clinic and plant pathogenic microorganisms, respectively. Methanol extract showed stronger and broader spectrum of antimicrobial activity as compared to hexane extract.

摘要

本研究旨在评估取自土耳其东安纳托利亚地区的一年生草本植物——庭园鼠尾草的甲醇提取物和己烷提取物的抗菌活性,该植物在当地作为传统民间药物用于治疗各种传染病和病症。采用纸片扩散法测试了这些提取物对属于55种细菌的147株实验室菌株以及1种酵母和4种真菌的31个分离株的抗菌活性。结果表明,庭园鼠尾草的己烷提取物没有抗真菌活性,但对三种芽孢杆菌属的四株菌株有抗菌活性,而庭园鼠尾草的甲醇提取物具有抗念珠菌和抗菌作用。在浓度为300μg/ml时,它抑制了11种细菌的23株菌株和白色念珠菌的6个分离株的生长。庭园鼠尾草对其余测试的微生物(83%)没有抗菌活性,这些微生物分别包括大多数临床致病微生物和所有植物致病微生物。与己烷提取物相比,甲醇提取物表现出更强且更广谱的抗菌活性。

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