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急性脊髓损伤的皮质类固醇给药:创伤医疗主任和紧急医疗系统医师顾问的当前实践

Administration of corticosteroids for acute spinal cord injury: the current practice of trauma medical directors and emergency medical system physician advisors.

作者信息

Peter Vellman W, Hawkes Allison P, Lammertse Daniel P

机构信息

Emergency Department, St. Anthony Central Hospital, Denver, CO 80204, USA.

出版信息

Spine (Phila Pa 1976). 2003 May 1;28(9):941-7; discussion 947. doi: 10.1097/01.BRS.0000058708.46933.3D.

Abstract

OBJECTIVE

In 1997, the results from the Third National Acute Spinal Cord Injury Study (NASCIS 3) were published. We undertook the present study to determine the treatment protocols for patients with spinal cord injuries in Colorado and assess whether there were any barriers to the administration of corticosteroids.

STUDY DESIGN

Cross-sectional.

METHODS

In May 1999, surveys were mailed to every trauma facility medical director and emergency medical system physician advisor in the state. Physicians were asked to provide information about their facilities' or agencies' current practice(s) for administering steroids to patients with spinal cord injuries. They were also asked about their opinion on whether the data on corticosteroid treatment for spinal cord injury support its use.

RESULTS

Ninety-eight percent (39 out of 41) of the medical directors who responded and treat patients with spinal cord injuries said that their facilities do administer steroids to those patients. Fourteen percent reported following the NASCIS 3 protocol; 75%, the NASCIS 2 protocol. About half of the medical directors were either uncertain or did not believe that the data regarding the corticosteroid treatment for spinal cord injury supported its use. The majority of physician advisors responded that they do not authorize the administration of corticosteroids to patients with spinal cord injuries in the field, primarily because of short transport times.

CONCLUSIONS

Our study demonstrated relatively poor compliance with the NASCIS 3 protocol, but good compliance with the NASCIS 2 protocol. There was skepticism about the efficacy of corticosteroid treatment among some Colorado physicians that treat patients with spinal cord injuries acutely; however, this does not completely explain the findings.

摘要

目的

1997年,第三次全国急性脊髓损伤研究(NASCIS 3)结果发表。我们开展本研究以确定科罗拉多州脊髓损伤患者的治疗方案,并评估使用皮质类固醇是否存在任何障碍。

研究设计

横断面研究。

方法

1999年5月,向该州每个创伤机构的医疗主任和紧急医疗系统医师顾问邮寄调查问卷。要求医师提供有关其机构目前对脊髓损伤患者使用类固醇的做法的信息。还询问了他们对脊髓损伤皮质类固醇治疗数据是否支持其使用的看法。

结果

回复并治疗脊髓损伤患者的医疗主任中有98%(41人中有39人)表示他们的机构确实对这些患者使用类固醇。14%报告遵循NASCIS 3方案;75%遵循NASCIS 2方案。约一半的医疗主任不确定或不认为脊髓损伤皮质类固醇治疗的数据支持其使用。大多数医师顾问回复说,他们不在现场授权对脊髓损伤患者使用皮质类固醇,主要原因是转运时间短。

结论

我们的研究表明对NASCIS 3方案的依从性相对较差,但对NASCIS 2方案的依从性良好。一些在科罗拉多州急性治疗脊髓损伤患者的医师对皮质类固醇治疗的疗效持怀疑态度;然而,这并不能完全解释研究结果。

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