丘疹性脐凹性环状肉芽肿。4例儿科病例报告。
Papular umbilicated granuloma annulare. A report of four pediatric cases.
作者信息
Lucky A W, Prose N S, Bove K, White W L, Jorizzo J L
机构信息
Division of Pediatric Dermatology, Children's Hospital Medical Center, Cincinnati, Ohio.
出版信息
Arch Dermatol. 1992 Oct;128(10):1375-8.
BACKGROUND
Granuloma annulare is a common skin condition usually presenting as annular plaques composed of intradermal papules. Variants such as disseminated, subcutaneous, and perforating have been described. In this article, the clinical and histologic features of a distinct papular umbilicated form of granuloma annulare are described.
OBSERVATIONS
Four boys aged 5 to 9 years presented with papular, umbilicated, flesh-colored papules limited to the dorsa of the hands and fingers. Histologically there were unusually distributed but typical features of granuloma annulare, including well-demarcated areas of necrobiosis of collagen, localized beneath areas of epidermal thinning and parakeratosis. There was no perforation.
CONCLUSIONS
Papular umbilicated granuloma annulare appears to be a distinct variant that may be difficult to diagnose because of its unique clinical and histologic features.
背景
环状肉芽肿是一种常见的皮肤疾病，通常表现为由皮内丘疹组成的环状斑块。已描述了多种变体，如播散性、皮下型和穿通型。本文描述了一种独特的丘疹脐凹型环状肉芽肿的临床和组织学特征。
观察结果
4名年龄在5至9岁的男孩出现丘疹、脐凹状、肉色丘疹，局限于手背和手指。组织学上，有环状肉芽肿异常分布但典型的特征，包括胶原坏死区域界限清晰，位于表皮变薄和角化不全区域下方。无穿通现象。
结论
丘疹脐凹型环状肉芽肿似乎是一种独特的变体，因其独特的临床和组织学特征可能难以诊断。
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