细菌蛋白毒素如何进入细胞；部分解折叠在膜转位中的作用。
How bacterial protein toxins enter cells; the role of partial unfolding in membrane translocation.
作者信息
London E
机构信息
Department of Biochemistry and Cell Biology, State University of New York, Stony Brook 11794-5215.
出版信息
Mol Microbiol. 1992 Nov;6(22):3277-82. doi: 10.1111/j.1365-2958.1992.tb02195.x.
Abstract
Bacterial protein toxins translocate across membranes by processes that are still mysterious. Studies on diphtheria toxin have shown that partial unfolding processes play a major role in toxin membrane insertion and translocation. Similar unfolding behaviour is seen with other bacterial toxins. The lessons gained from this behaviour allow us to propose novel mechanisms for toxin translocation.
摘要
细菌蛋白毒素通过仍然神秘的过程跨膜转运。对白喉毒素的研究表明，部分解折叠过程在毒素膜插入和转运中起主要作用。其他细菌毒素也有类似的解折叠行为。从这种行为中获得的经验教训使我们能够提出毒素转运的新机制。
Zotero 插件