新生儿感染的诊断标志物。
Diagnostic markers of infection in neonates.
作者信息
Ng P C
机构信息
Department of Paediatrics, Prince of Wales Hospital, Hong Kong.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2004 May;89(3):F229-35. doi: 10.1136/adc.2002.023838.
Abstract
Diagnostic markers of infection are useful indicators of neonatal sepsis. Serial measurements of infection markers can improve diagnostic sensitivity, and the use of multiple markers can enhance diagnostic accuracy. Current evidence suggests that promising markers may be useful for early termination of antimicrobial treatment, but none of the current diagnostic tests are sensitive and specific enough to influence the clinical decision for withholding antibiotic treatment at the onset of suspected infection.
摘要
感染的诊断标志物是新生儿败血症的有用指标。对感染标志物进行系列检测可提高诊断敏感性，使用多种标志物可提高诊断准确性。目前的证据表明，有前景的标志物可能有助于早期终止抗菌治疗，但目前没有一种诊断测试的敏感性和特异性足以影响在疑似感染开始时停用抗生素治疗的临床决策。
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