闲聊；调控果蝇中的自噬

Chewing the fat; regulating autophagy in Drosophila.

作者信息

Grewal Savraj S, Saucedo Leslie J

机构信息

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 USA.

出版信息

Dev Cell. 2004 Aug;7(2):148-50. doi: 10.1016/j.devcel.2004.07.014.

DOI:10.1016/j.devcel.2004.07.014

PMID:15296710

Abstract

Autophagy is the major cellular process responsible for bulk cytoplasmic degradation. Two reports in this issue of Developmental Cell describe how both PI3 kinase and TOR signaling in Drosophila are critical for controlling autophagy in response to developmental and environmental cues.

摘要

自噬是负责大量细胞质降解的主要细胞过程。本期《发育细胞》中的两篇报道描述了果蝇中的PI3激酶和TOR信号传导如何在响应发育和环境线索时对控制自噬至关重要。