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[童年时期经历列宁格勒围城战的中老年人躯体疾病的特点]

[Peculiarities of somatic diseases in people of middle and old age survived Leningrad siege at childhood].

作者信息

Khoroshinina L P

出版信息

Adv Gerontol. 2004;14:55-65.

Abstract

The results of a study on peculiarities of development of some diseases in adult peoples survived the Leningrad siege at childhood are presented. The age- and sex-related differences in an incidence and clinical features of diseases are demonstrated. More frequent incidence of severe arterial hypertension, diabetes mellitus type 2, biliar calculite disease, chronic atrophic pangastritis, terminal stage of kidney failure, more early mortality, clinically unfavorable aortal atherosclerosis development, as well as atherosclerosis of coronary, brain and carotid artheria have been revealed. Specific histological and morphometric changes in kidney tissue of the patients at preclinical stage are demonstrated.

摘要

本文展示了一项关于童年时期经历列宁格勒围城战的成年人某些疾病发展特点的研究结果。研究表明了疾病发病率和临床特征在年龄和性别上的差异。研究发现重度动脉高血压、2型糖尿病、胆石症、慢性萎缩性胃炎、肾衰竭终末期的发病率更高,死亡率更早出现,主动脉粥样硬化在临床上发展不利,以及冠状动脉、脑动脉和颈动脉也出现了动脉粥样硬化。研究还展示了患者临床前期肾组织中特定的组织学和形态学变化。

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