Raz R, Chazan B, Dan M
Infectious Diseases Unit, Haemek Medical Center, Afula, Israel.
Harefuah. 2004 Dec;143(12):891-4, 909.
Cranberries have long been the focus of interest for their beneficial effects in preventing urinary tract infections (UTIs). Cranberries contain two compounds with anti-adherence properties, which prevent fimbriated E. coli from adhering to uroepithelial cells in the urinary tract. Approximately a dozen clinical trials have been performed testing the effects of cranberries on the urinary tract. However, these trials have a number of apparent limitations. Most importantly, the trials have used a wide variety of cranberry products, such as cranberry juice concentrate, juice cocktail, and cranberry capsules, and have employed different dosing regimens. Further research is required to clarify unanswered questions regarding the role of cranberries in protecting against UTI in general and in women with anatomical abnormalities in particular.
长期以来,蔓越莓因其在预防尿路感染(UTIs)方面的有益作用而备受关注。蔓越莓含有两种具有抗黏附特性的化合物,可防止有菌毛的大肠杆菌黏附于尿路中的尿路上皮细胞。大约进行了十二项临床试验来测试蔓越莓对尿路的影响。然而,这些试验存在一些明显的局限性。最重要的是,试验使用了多种蔓越莓产品,如浓缩蔓越莓汁、果汁鸡尾酒和蔓越莓胶囊,并采用了不同的给药方案。需要进一步研究以澄清关于蔓越莓在总体预防UTI以及特别是对有解剖结构异常的女性预防UTI方面尚未解答的问题。