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左旋布比卡因与罗哌卡因用于下肢骨科手术中腰大肌间隙阻滞和坐骨神经阻滞的比较。

Levobupivacaine versus ropivacaine in psoas compartment block and sciatic nerve block in orthopedic surgery of the lower extremity.

作者信息

Piangatelli C, De Angelis C, Pecora L, Recanatini F, Testasecca D

机构信息

Unit of Anesthesia and Resuscitation, Umberto I Hospital, Ancona, Italy.

出版信息

Minerva Anestesiol. 2004 Dec;70(12):801-7.

Abstract

AIM

The aim of this study was to compare the clinical profiles of psoas block and sciatic nerve block performed with either 0.5% levobupivacaine or 0.75% ropivacaine.

METHODS

With ethical committee approval and written informed consent 80 ASA physical status I-II patients, undergoing lower extremity surgery received intravenous premedication with midazolam (0.05 mg/kg) and atropine (0.01 mg/kg). Patients were randomly allocated to receive a lumbar plexus block with: Levobupivacaine Group (L) 30 ml of 0.5% levobupivacaine or Ropivacaine Group (R) 0.75% ropivacaine, and sciatic nerve block with: Group R 10 ml 0.75 ropivacaine or Group L 0.5% levobupivacaine. The onset time and duration of nerve block were evaluated.

RESULTS

The motor onset time was shorter in Group L than in Group R. The motor offset time was similar in the 2 groups, the time being slightly greater for Group R. Group L presented a higher difference of resolution to motor-sensitive block compared to Group R.

CONCLUSIONS

The differences between Groups L and R were characterised by: a faster motor onset time in Group L with a longer time between motor and sensitive resolution determining a lower demand for analgesic drugs postoperatively and greater support for motor control recovery.

摘要

目的

本研究旨在比较用0.5%左旋布比卡因或0.75%罗哌卡因进行腰大肌阻滞和坐骨神经阻滞的临床特征。

方法

经伦理委员会批准并获得书面知情同意后,80例接受下肢手术的美国麻醉医师协会(ASA)身体状况I-II级患者,静脉注射咪达唑仑(0.05 mg/kg)和阿托品(0.01 mg/kg)进行术前用药。患者被随机分配接受以下腰丛阻滞:左旋布比卡因组(L组),30 ml 0.5%左旋布比卡因;或罗哌卡因组(R组),0.75%罗哌卡因;以及以下坐骨神经阻滞:R组,10 ml 0.75%罗哌卡因;或L组,0.5%左旋布比卡因。评估神经阻滞的起效时间和持续时间。

结果

L组的运动起效时间比R组短。两组的运动消退时间相似,R组稍长。与R组相比,L组在运动敏感阻滞消退方面的差异更大。

结论

L组和R组之间的差异表现为:L组运动起效时间更快,运动和感觉消退之间的时间更长,这决定了术后对镇痛药的需求更低,对运动控制恢复的支持更大。

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