[AGO卵巢器官委员会的质量保证计划（QS-OVAR）：2001年德国的护理模式与实际情况]

[The Quality Assurance Program of the AGO Organkommission OVAR (QS-OVAR): Pattern of Care and Reality in Germany 2001].

作者信息

du Bois A, Rochon J, Lamparter C, Pfisterer J

机构信息

Klinik für Gynäkologie & Gynäkologische Onkologie, HSK Wiesbaden, Germany.

出版信息

Zentralbl Gynakol. 2005 Feb;127(1):9-17. doi: 10.1055/s-2005-836289.

DOI:10.1055/s-2005-836289

PMID:15702446

Abstract

PURPOSE

To evaluate pattern and quality of care for ovarian cancer in Germany and analyze adherence to treatment guidelines as well as prognostic factors for survival.

METHODS

Nationwide survey including patients with histological proven invasive epithelial ovarian cancer diagnosed in the third quarter 2001 including descriptive analysis of pattern of surgical care and systemic treatment in early (FIGO I-IIA) and advanced (FIGO IIB-IV) ovarian cancer and both univariate and multivariate analysis of prognostic factors.

RESULTS

476, representing more than one third of all patients diagnosed in Q III 2001 in Germany were included. Standard care according to German guidelines was provided to only 35.5 % of patients with early ovarian cancer. Optimal debulking was reported for 61.4 % patients with FIGO stages IIB-IV. Recommended platinum-paclitaxel chemotherapy was given to 3 out of 4 patients in advanced disease. Multivariate analysis showed advanced stage, poor performance status, co-morbidity, ascites, postoperative tumor residuals, and less than standard care to be associated with inferior survival.

CONCLUSIONS

Adherence to treatment guidelines showed remarkable variety among German hospitals indicating options and need for improvement.

摘要

目的

评估德国卵巢癌的治疗模式和质量，分析治疗指南的遵循情况以及生存的预后因素。

方法

全国性调查，纳入2001年第三季度确诊的组织学确诊的侵袭性上皮性卵巢癌患者，包括对早期（FIGO I-IIA）和晚期（FIGO IIB-IV）卵巢癌手术治疗和全身治疗模式的描述性分析，以及预后因素的单因素和多因素分析。

结果

纳入了476例患者，占2001年第三季度德国所有确诊患者的三分之一以上。仅35.5%的早期卵巢癌患者接受了德国指南规定的标准治疗。FIGO IIB-IV期患者中61.4%报告进行了最佳肿瘤细胞减灭术。晚期疾病患者中四分之三接受了推荐的铂类-紫杉醇化疗。多因素分析显示，晚期、体能状态差、合并症、腹水、术后肿瘤残留以及未接受标准治疗与较差的生存率相关。