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基于人群的骨密度测量数据库的构建与验证

Construction and validation of a population-based bone densitometry database.

作者信息

Leslie William D, Caetano Patricia A, Macwilliam Leonard R, Finlayson Gregory S

机构信息

Department of Medicine (C5121), St. Boniface General Hospital, 409 Tache Avenue, Winnipeg, Canada R2H 2A6.

出版信息

J Clin Densitom. 2005 Spring;8(1):25-30. doi: 10.1385/jcd:8:1:025.

Abstract

Utilization of dual-energy X-ray absorptiometry (DXA) for the initial diagnostic assessment of osteoporosis and in monitoring treatment has risen dramatically in recent years. Population-based studies of the impact of DXA and osteoporosis remain challenging because of incomplete and fragmented test data that exist in most regions. Our aim was to create and assess completeness of a database of all clinical DXA services and test results for the province of Manitoba, Canada and to present descriptive data resulting from testing. A regionally based bone density program for the province of Manitoba, Canada was established in 1997. Subsequent DXA services were prospectively captured in a program database. This database was retrospectively populated with earlier DXA results dating back to 1990 (the year that the first DXA scanner was installed) by integrating multiple data sources. A random chart audit was performed to assess completeness and accuracy of this dataset. For comparison, testing rates determined from the DXA database were compared with physician administrative claims data. There was a high level of completeness of this database (>99%) and accurate personal identifier information sufficient for linkage with other health care administrative data (>99%). This contrasted with physician billing data that were found to be markedly incomplete. Descriptive data provide a profile of individuals receiving DXA and their test results. In conclusion, the Manitoba bone density database has great potential as a resource for clinical and health policy research because it is population based with a high level of completeness and accuracy.

摘要

近年来,双能X线吸收测定法(DXA)在骨质疏松症初始诊断评估及治疗监测中的应用急剧增加。由于大多数地区存在不完整和零散的检测数据,基于人群的DXA和骨质疏松症影响研究仍具有挑战性。我们的目标是创建并评估加拿大曼尼托巴省所有临床DXA服务和检测结果数据库的完整性,并展示检测得出的描述性数据。1997年在加拿大曼尼托巴省建立了一个基于地区的骨密度项目。随后,DXA服务被前瞻性地录入项目数据库。通过整合多个数据源,该数据库被追溯性地填充了可追溯至1990年(第一台DXA扫描仪安装的年份)的早期DXA结果。进行了随机图表审核以评估该数据集的完整性和准确性。为作比较,将从DXA数据库确定的检测率与医生管理索赔数据进行了比较。该数据库具有高度的完整性(>99%),且有足够准确的个人识别信息用于与其他医疗管理数据进行关联(>99%)。这与发现明显不完整的医生计费数据形成对比。描述性数据提供了接受DXA检测的个体及其检测结果的概况。总之,曼尼托巴骨密度数据库作为临床和卫生政策研究的资源具有巨大潜力,因为它基于人群,具有高度的完整性和准确性。

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