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爱沙尼亚、芬兰和瑞典对阻塞性气道疾病的不同分类。

Different labelling of obstructive airway diseases in Estonia, Finland, and Sweden.

作者信息

Pallasaho Paula, Meren Mari, Raukas-Kivioja Aet, Rönmark Eva

机构信息

Department of Medicine, Division of Respiratory Medicine and Allergology, Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

Eur J Epidemiol. 2005;20(12):975-83. doi: 10.1007/s10654-005-4117-6.

Abstract

Large differences in prevalence of asthma have been reported between westernised countries and the former Eastern European countries, and still no consensus about the reasons for the differences exists. The aim of this study was to assess diagnostic labelling of obstructive airway diseases, comparing subjects with respiratory symptoms and the diagnoses obtained in Estonia, Finland, and Sweden. A postal questionnaire was sent to population-based random samples, and 44,483 (76%) answers were obtained from the 58,661 invited in 1996. Among men, current smoking was most common in Estonia, 60%, followed by Finland, 39%, and Sweden, 28%. In all three countries, 30% of women were current smokers. Most respiratory symptoms including wheezing were most common in Estonia, also among non-smokers. The prevalence of asthma was 2.0% and chronic bronchitis 10.7% in Estonia, while the opposite was found in Sweden with an asthma prevalence of 7.8% and a chronic bronchitis prevalence of 3.1%. The pattern in Finland was similar to that of Sweden. The same differences between the three countries were found also among young subjects. The total proportion of diagnosed obstructive lung diseases in subjects with respiratory symptoms was similar, but the diagnosis of asthma was considerably more common in Finland and Sweden. Chronic bronchitis was favoured in Estonia, also among young adults irrespectively of what symptoms were present. In a multivariate model with correction for confounders, the risk (OR) for having a diagnosis of asthma was 5.65 (95% CI: 4.86-6.56) when living in Sweden, and 3.51 (95% CI: 3.00-4.12) in Finland, whereas risk for chronic bronchitis was 0.28 (0.25-0.31) and 0.22 (0.19-0.25), respectively, compared to Estonia. The study indicates differences in diagnostic practices of obstructive lung diseases between the three countries.

摘要

据报道,西方国家和前东欧国家在哮喘患病率上存在巨大差异,且对于造成这些差异的原因仍未达成共识。本研究的目的是评估阻塞性气道疾病的诊断标签,比较有呼吸道症状的受试者以及在爱沙尼亚、芬兰和瑞典所获得的诊断结果。向基于人群的随机样本发放了邮政问卷,在1996年受邀的58,661人中获得了44,483份(76%)回复。在男性中,当前吸烟者比例在爱沙尼亚最高,为60%,其次是芬兰,为39%,瑞典为28%。在所有三个国家,30%的女性为当前吸烟者。包括喘息在内的大多数呼吸道症状在爱沙尼亚最为常见,在非吸烟者中也是如此。爱沙尼亚的哮喘患病率为2.0%,慢性支气管炎患病率为10.7%,而在瑞典情况则相反,哮喘患病率为7.8%,慢性支气管炎患病率为3.1%。芬兰的情况与瑞典相似。在年轻受试者中也发现了这三个国家之间的相同差异。有呼吸道症状的受试者中被诊断为阻塞性肺病的总比例相似,但哮喘诊断在芬兰和瑞典更为常见。慢性支气管炎在爱沙尼亚更为常见,在年轻成年人中也是如此,无论其有何种症状。在对混杂因素进行校正的多变量模型中,居住在瑞典时被诊断为哮喘的风险(OR)为5.65(95%CI:4.86 - 6.56),在芬兰为3.51(95%CI:3.00 - 4.12),而与爱沙尼亚相比,慢性支气管炎的风险分别为0.28(0.25 - 0.31)和0.22(0.19 - 0.25)。该研究表明这三个国家在阻塞性肺病诊断实践上存在差异。

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