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[绝经后女性的便秘]

[Constipation in postmenopausal women].

作者信息

Oliveira Simone Caetano Morale de, Pinto-Neto Aarão Mendes, Conde Délio Marques, Góes Juvenal Ricardo Navarro, Santos-Sá Danielle, Fonsechi-Carvasan Gislaine A, Costa-Paiva Lúcia

机构信息

Departamento de Tocoginecologia, Centro de Atenção Integral à Saúde da Mulher, Universidade de Campinas, Campinas, SP.

出版信息

Rev Assoc Med Bras (1992). 2005 Nov-Dec;51(6):334-41. doi: 10.1590/s0104-42302005000600017. Epub 2006 Jan 18.

Abstract

OBJECTIVES

To investigate the prevalence and factors associated with constipation in postmenopausal women and evaluate the level of agreement between different diagnostic criteria.

METHODS

A cross-sectional study was conducted with 100 postmenopausal women more than 45 old. The Rome II criteria, stool frequency per week and patient self-evaluation were the diagnostic criteria applied. Social demographic and clinical characteristics with their descriptive analysis were assessed. Subsequently, kappa (ê) statistics was used to assess the level of agreement between diagnostic criteria. The association between constipation and its possible determinants was studied by bivariate and multivariate analyses, using the prevalence ratio (PR). The confidence interval was set at 95% (95% CI).

RESULTS

The mean age of participants was 58.9+/-5.9 years (range, 46-76 years). The prevalence of constipation was 47%, 37% and 26%, according to patient self-evaluation, the Rome II criteria and < 3 bowel movements per week, respectively. The best agreement found was between patient self-evaluation and the Rome II criteria (k: 0.63; 95% CI: 0.48-0.78). After multivariate analysis, the history of perianal surgery (PR: 2.69; 95% CI: 1.03-7.01), according to the Rome II criteria; the presence of hemorrhoids, according to stool frequency (PR: 2.53; 95% CI: 1.16-5.51) and patient self-evaluation (PR: 1.78; 95% CI: 1.01-3.15) were associated with constipation.

CONCLUSIONS

Prevalence of constipation in postmenopausal women was high. Agreement between diagnostic criteria ranged from moderate to good. History of perianal surgery and presence of hemorrhoids were associated with constipation.

摘要

目的

调查绝经后女性便秘的患病率及其相关因素,并评估不同诊断标准之间的一致性水平。

方法

对100名45岁以上的绝经后女性进行了一项横断面研究。采用罗马II标准、每周排便次数和患者自我评估作为诊断标准。评估了社会人口统计学和临床特征及其描述性分析。随后,使用kappa(κ)统计量评估诊断标准之间的一致性水平。采用患病率比(PR),通过双变量和多变量分析研究便秘与其可能的决定因素之间的关联。置信区间设定为95%(95%CI)。

结果

参与者的平均年龄为58.9±5.9岁(范围46 - 76岁)。根据患者自我评估、罗马II标准和每周排便次数<3次,便秘的患病率分别为47%、37%和26%。发现患者自我评估与罗马II标准之间的一致性最佳(κ:0.63;95%CI:0.48 - 0.78)。多变量分析后,根据罗马II标准,肛周手术史(PR:2.69;95%CI:1.03 - 7.01);根据排便频率,存在痔疮(PR:2.53;95%CI:1.16 - 5.51)以及患者自我评估(PR:1.78;95%CI:1.01 - 3.15)与便秘相关。

结论

绝经后女性便秘的患病率较高。诊断标准之间的一致性从中度到良好不等。肛周手术史和痔疮的存在与便秘相关。

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