Park Jae-Hyun, Yoon Seok-Jun, Lee Hee-Young, Cho Hee-Sook, Lee Jin-Yong, Eun Sang-Jun, Park Jong-Hyock, Kim Yoon, Kim Yong-Ik, Shin Young-Soo
Department of Health Policy and Management, Seoul National University College of Medicine.
J Prev Med Public Health. 2006 Jan;39(1):39-45.
This study estimated the burden of disease especially caused by psychiatric disorders in Korea by using DALY, a composite indicator that was recently developed by the Global Burden of Disease study group.
First, 11 of the major psychiatric disorders in Korea were selected based on the ICD-10. Second, the burden of disease due to premature death was estimated by using YLLs (years of life lost due to premature death). Third, for the calculation of the YLD (years lived with disability), the following parameters were estimated in the formula: the incidence rate, the prevalence rate and the disability weight of each psychiatric disorder. Last, we estimated the DALY of the psychiatric disorders by adding the YLLs and YLDs.
The burden of psychiatric disorder per 100,000 people was attributed mainly to unipolar major depression (1,278 person-years), schizophrenia (638 person-years) and alcohol use disorder (287 person-years). For males, schizophrenia (596 person-years) and alcohol use disorder (491 person-years) caused the highest burden. For females, unipolar major depression (1,749 person-years) and schizophrenia (680 person-years) cause the highest burden. As analyzed by gender and age group, alcohol use disorder causes a higher burden than schizophrenia in men aged 40 years and older. For females, unipolar major depression causes the highest burden in all age groups.
We found that each of the psychiatric disorders that cause the highest burden is different according to gender and age group. This study's results can provide a rational basis to plan a national health policy regarding the burden of disease caused by psychiatric disorders.
本研究使用伤残调整生命年(DALY)这一由全球疾病负担研究小组最近开发的综合指标,估算韩国尤其是精神障碍所致的疾病负担。
首先,根据国际疾病分类第10版(ICD - 10)选择韩国11种主要精神障碍。其次,使用早死所致生命年损失(YLLs)估算早死导致的疾病负担。第三,为计算伤残所致生命年(YLD),在公式中估算以下参数:每种精神障碍的发病率、患病率和伤残权重。最后,通过将YLLs和YLDs相加估算精神障碍的DALY。
每10万人中精神障碍负担主要归因于单相重度抑郁症(1278人年)、精神分裂症(638人年)和酒精使用障碍(287人年)。对于男性,精神分裂症(596人年)和酒精使用障碍(491人年)造成的负担最高。对于女性,单相重度抑郁症(1749人年)和精神分裂症(680人年)造成的负担最高。按性别和年龄组分析,40岁及以上男性中,酒精使用障碍造成的负担高于精神分裂症。对于女性,单相重度抑郁症在所有年龄组造成的负担最高。
我们发现,根据性别和年龄组,造成最高负担的每种精神障碍各不相同。本研究结果可为规划关于精神障碍所致疾病负担的国家卫生政策提供合理依据。