Gorelick Marc H, Meurer John R, Walsh-Kelly Christine M, Brousseau David C, Grabowski Laura, Cohn Jennifer, Kuhn Evelyn M, Kelly Kevin J
Department of Pediatrics, Division of Emergency Medicine, Medical College of Wisconsin, Children's Hospital of Wisconsin and Children's Research Institute, Milwaukee, Wisconsin, USA.
Pediatrics. 2006 Apr;117(4 Pt 2):S127-34. doi: 10.1542/peds.2005-2000J.
We sought to study the impact of emergency department (ED)-based intensive primary care linkage and initiation of asthma case management on long-term, patient-oriented outcomes for children with an asthma exacerbation.
Our study was a randomized, 3-arm, parallel-group, single-blind clinical trial. Children aged 2 through 17 years treated in a pediatric ED for acute asthma were randomly assigned to standard care (group 1), including patient education, a written care plan, and instructions to follow up with the primary care provider within 7 days, or 1 of 2 interventions. Group 2 received standard care plus assistance with scheduling follow-up, while group 3 received the above interventions, plus enrollment in a case management program.
The primary outcome was the proportion of children having an ED visit for asthma within 6 months. Other outcomes included change in quality-of-life score and controller-medication use.
Three hundred fifty-two children were enrolled; 78% completed follow-up, 69% were black, and 70% had persistent asthma. Of the children, 37.8% had a subsequent ED visit for asthma, with no difference among the treatment groups (group 1: 38.4%; group 2, 39.2%; group 3, 35.8%). Children in all groups had a substantial, but similar, increase in their quality-of-life score. Controller-medication use increased from 69.4% to 81.4%, with no difference among the groups.
ED-based attempts to improve primary care linkage or initiate case management are no more effective than our standard ED care in improving subsequent asthma outcomes over a 6-month period.
我们试图研究基于急诊科(ED)的强化初级保健联系以及启动哮喘病例管理对哮喘急性加重儿童的长期、以患者为导向的结局的影响。
我们的研究是一项随机、三臂、平行组、单盲临床试验。在儿科急诊科接受急性哮喘治疗的2至17岁儿童被随机分配至标准治疗组(第1组),包括患者教育、书面护理计划以及在7天内与初级保健提供者进行随访的指示,或两种干预措施之一。第2组接受标准治疗并获得随访安排协助,而第3组接受上述干预措施,并加入病例管理计划。
主要结局是6个月内因哮喘到急诊科就诊的儿童比例。其他结局包括生活质量评分变化和控制药物使用情况。
共纳入352名儿童;78%完成随访,69%为黑人,70%患有持续性哮喘。在这些儿童中,37.8%随后因哮喘到急诊科就诊,各治疗组之间无差异(第1组:38.4%;第2组,39.2%;第3组,35.8%)。所有组的儿童生活质量评分均有显著但相似的提高。控制药物的使用从69.4%增加到81.4%,各组之间无差异。
在6个月期间,基于急诊科改善初级保健联系或启动病例管理的尝试在改善后续哮喘结局方面并不比我们的标准急诊科护理更有效。