源自金刚烷甘氨酸的四羧基二铑作为卡宾反应的手性催化剂。
Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.
作者信息
Reddy Ravisekhara P, Lee Gene H, Davies Huw M L
机构信息
Department of Chemistry, University at Buffalo, State University of New York, Buffalo, New York 14260-3000, USA.
出版信息
Org Lett. 2006 Aug 3;8(16):3437-40. doi: 10.1021/ol060893l.
PMID:16869629
Abstract
[reaction: see text] The dirhodium tetracarboxylate, Rh2(S-PTAD)4, derived from adamantylglycine, is a very effective chiral catalyst for carbenoid reactions. High asymmetric induction was obtained in Rh2(S-PTAD)4-catalyzed intramolecular C-H insertion (94% ee), intermolecular cyclopropanation (99% ee), and intermolecular C-H insertion (92% ee).
摘要
[反应：见正文] 由金刚烷基甘氨酸衍生得到的四羧酸二铑Rh2(S-PTAD)4是一种用于类卡宾反应的非常有效的手性催化剂。在Rh2(S-PTAD)4催化的分子内C-H插入反应（对映体过量率94%）、分子间环丙烷化反应（对映体过量率99%）和分子间C-H插入反应（对映体过量率92%）中获得了高不对称诱导效果。
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