南非林波波省文达地区溶组织内阿米巴和迪斯帕内阿米巴的流行情况及种类分布
Prevalence and species distribution of E. Histolytica and E. Dispar in the Venda region, Limpopo, South Africa.
作者信息
Samie Amidou, Obi Larry C, Bessong Pascal O, Stroup Suzanne, Houpt Eric, Guerrant Richard L
机构信息
Department of Microbiology, University of Venda, Thohoyandou, South Africa.
出版信息
Am J Trop Med Hyg. 2006 Sep;75(3):565-71.
The prevalence and species distribution of Entamoeba histolytica and E. dispar in the Venda region were determined in stool samples collected from public hospitals and primary schools by ELISA and a nested polymerase chain reaction (PCR). E. histolytica was detected in 37/197 (18.8%) and 1/47 (2.1%) samples, whereas 50/197 (25.3%) and 4/47 (8.5%) had E. dispar in the hospitals and schools, respectively. The age groups most infected were 0-2 (33%) years followed by 20-29 years (27%). E. histolytica was significantly associated with diarrhea (77.4% versus 22.6%; chi 2 = 39.48, P < 0.05), and with the presence of lactoferrin (85.7% versus 14.2%) in the stools, indicating intestinal inflammation (chi 2 = 29.605, P < 0.05). E. histolytica was found in 5 (16.12%) of the 31 HIV-positive individuals and in 33 (15.5%) of the 213 HIV-negative individuals. E. histolytica infections are common in the Venda region and are associated with diarrhea and intestinal inflammation.
通过酶联免疫吸附测定（ELISA）和巢式聚合酶链反应（PCR），对从公立医院和小学采集的粪便样本进行检测，以确定在文达地区溶组织内阿米巴和迪斯帕内阿米巴的流行情况及种类分布。在医院样本中，197份样本中有37份（18.8%）检测到溶组织内阿米巴，47份样本中有1份（2.1%）检测到；在学校样本中，197份样本中有50份（25.3%）检测到迪斯帕内阿米巴，47份样本中有4份（8.5%）检测到。感染率最高的年龄组是0至2岁（33%），其次是20至29岁（27%）。溶组织内阿米巴与腹泻显著相关（77.4%对22.6%；卡方 = 39.48，P < 0.05），且与粪便中乳铁蛋白的存在相关（85.7%对14.2%），表明存在肠道炎症（卡方 = 29.605，P < 0.05）。在31名HIV阳性个体中有5名（16.12%）检测到溶组织内阿米巴，在213名HIV阴性个体中有33名（15.5%）检测到。溶组织内阿米巴感染在文达地区很常见，且与腹泻和肠道炎症有关。
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