巴西贫困城镇中匐行疹的纵向研究。

A longitudinal study on cutaneous larva migrans in an impoverished Brazilian township.

机构信息

Mandacaru Foundation, Rua José Vilar de Andrade 257, Fortaleza, CE 60833-830, Brazil.

出版信息

Travel Med Infect Dis. 2003 Nov;1(4):213-8. doi: 10.1016/j.tmaid.2003.10.003.

DOI:10.1016/j.tmaid.2003.10.003

PMID:17291920

Abstract

BACKGROUND

The objective of this study was to describe the clinical pathology and seasonal variation of cutaneous larva migrans (CLM) in an impoverished community.

METHOD

A representative sample of the population of a poor urban neighbourhood in Fortaleza, northeast Brazil, was examined for CLM four times during a period of eleven months.

RESULTS

In total, 4107 individuals were examined. Sixty-three individuals were diagnosed to have CLM with a total of 132 larval tracks. The prevalence varied from 3.1% (95% CI: 2.2-4.3) in the middle of the rainy season to 0.2% (95% CI: 0.0-0.9) in the peak of the dry season. This corresponds to an incidence of 1841 cases of CLM per 10,000 inhabitants per year. The male sex was significantly more often affected (P<0.01). Eighty-three percent of the lesions were located at the trunk, legs or feet. Moderate or severe itching was present in all patients; 31.2% complained of insomnia due to itching, and 21% of the lesions were superinfected.

CONCLUSIONS

CLM is a common parasitic skin disease in this deprived community, it is associated with significant morbidity, and its occurrence varies according to the rainfall.

摘要

背景

本研究旨在描述贫困社区中皮肤幼虫移行症（CLM）的临床病理学和季节性变化。

方法

在巴西东北部福塔莱萨的一个贫穷城市社区，在十一个月的时间内，四次对人群进行了 CLM 检查。

结果

共检查了 4107 人。63 人被诊断患有 CLM，共有 132 条幼虫痕迹。患病率在雨季中期为 3.1%（95%CI：2.2-4.3），在旱季高峰期为 0.2%（95%CI：0.0-0.9）。这相当于每年每 10000 名居民中有 1841 例 CLM 病例。男性受影响的比例明显更高（P<0.01）。83%的病变位于躯干、腿部或脚部。所有患者均有中度或重度瘙痒；31.2%因瘙痒而失眠，21%的病变发生继发感染。