病毒生物学与纳米技术的结合：纳米医学中的新应用。

Combination of viral biology and nanotechnology: new applications in nanomedicine.

作者信息

Saini Vaibhav, Zharov Vladimir P, Brazel Christopher S, Nikles David E, Johnson Duane T, Everts Maaike

机构信息

Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-2180, USA.

出版信息

Nanomedicine. 2006 Sep;2(3):200-6. doi: 10.1016/j.nano.2006.07.002.

DOI:10.1016/j.nano.2006.07.002

PMID:17292143

Abstract

Viruses are well known for their ability to cause disease, but their beneficial usefulness as vectors for gene therapy have been noted as well. As an extension of their use in a gene therapy context, their combination with nanotechnology is starting to benefit many areas of science and medicine. These include nanofabrication and medical diagnostics, to name a few, as well as viro-nanotherapy, here defined as the combination of viral biology with nanotechnology to create new therapeutic avenues to treat disease. This review provides examples of areas wherein viruses in combination with nanotechnology are being used to either advance scientific knowledge or accelerate the development of new diagnostics and therapeutics for human pathological conditions.

摘要

病毒以其致病能力而闻名，但它们作为基因治疗载体的有益用途也已被注意到。作为其在基因治疗背景下应用的延伸，它们与纳米技术的结合开始使许多科学和医学领域受益。其中包括纳米制造和医学诊断等，还有病毒纳米疗法，这里定义为病毒生物学与纳米技术相结合以创造治疗疾病的新途径。本综述提供了一些领域的例子，其中病毒与纳米技术相结合被用于推进科学知识或加速针对人类病理状况的新诊断和治疗方法的开发。