Palmieri B, Sblendorio V
Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy.
Eur Rev Med Pharmacol Sci. 2007 Jan-Feb;11(1):27-54.
Oxygen-free radicals, more generally known as reactive oxygen species (ROS) along with nitrogen species (RNS) are well recognised for playing a dual role both deleterious and beneficial species. The cumulative generation of ROS/RNS through either endogenous or exogenous insults is termed oxidative stress and is common for many types of diseases that are linked with altered redox regulation of cellular signalling pathways.
氧自由基,更普遍地称为活性氧(ROS)以及氮类物质(RNS),因其兼具有害和有益双重作用而广为人知。通过内源性或外源性损伤累积产生的ROS/RNS被称为氧化应激,这在许多与细胞信号通路氧化还原调节改变相关的疾病类型中很常见。