Kakkar V, Kaur D, Chopra K, Kaur A, Kaur I P
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.
Maturitas. 2007 Jul 20;57(3):306-14. doi: 10.1016/j.maturitas.2007.02.026. Epub 2007 Apr 3.
To study the variation of the menopause rating scale (MRS) scores with age, working/non-working and educated/uneducated status in a cohort of north-Indian subpopulation and to look for the possible reasons for the incurred variations. MRS is a well-known and validated instrument for assessing the frequency and intensity of menopausal symptoms.
A menopause clinic was organized in collaboration with a primary care centre (under the guidance of a gynecologist). A random sample of 208 women aged 35-65 years participated in the study. The MRS scale, a self-administered standardized questionnaire was applied with additional patient related information (age at menopause, level of education, working/non-working and exercising or not).
The results were evaluated for psychological (P), somatic (S), and urogenital (U) symptoms. The average age at which menopause set in, in the cohort was found to be 48.7+/-2.3 years (46.4-51 years). Based on the average age at the menopause, the cohort was divided into peri (35-45), menopausal/early menopause (46-51) and the postmenopausal (52-65) groups. A significantly higher % of perimenopausal women (36%) showed a P score of > or =7; while a higher % of postmenopausal showed S score and U score > or =7 (>40%; p< or =0.001). Working women seem to suffer more from psychological symptoms whereas non-working women showed a greater incidence of somatic symptoms. Educated women showed a lower incidence of psychological and somatic symptoms.
Present study indicates that age, level of education and working/non-working status (in a group of women with same socio-cultural background) may also contribute to significant variations in menopausal symptoms.
研究印度北部亚人群队列中绝经评分量表(MRS)得分随年龄、工作/非工作状态以及受教育/未受教育状态的变化情况,并探寻产生这些变化的可能原因。MRS是一种用于评估绝经症状发生频率和严重程度的知名且经过验证的工具。
在一家初级保健中心(在妇科医生的指导下)合作组织了一家绝经诊所。随机抽取了208名年龄在35 - 65岁的女性参与研究。应用MRS量表,这是一份自我管理的标准化问卷,并收集了额外的患者相关信息(绝经年龄、教育程度、工作/非工作状态以及是否锻炼)。
对心理(P)、躯体(S)和泌尿生殖系统(U)症状的结果进行了评估。该队列中绝经开始的平均年龄为48.7±2.3岁(46.4 - 51岁)。根据绝经的平均年龄,该队列被分为围绝经期(35 - 45岁)、绝经/早期绝经(46 - 51岁)和绝经后期(52 - 65岁)组。围绝经期女性中,有显著更高比例(36%)的P得分≥7;而绝经后期女性中,S得分和U得分≥7的比例更高(>40%;p≤0.001)。职业女性似乎更容易出现心理症状,而非职业女性出现躯体症状的发生率更高。受过教育的女性心理和躯体症状的发生率较低。
本研究表明,年龄、教育程度和工作/非工作状态(在具有相同社会文化背景的女性群体中)也可能导致绝经症状出现显著差异。