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[变形杆菌属细菌:特征与毒力因子]

[Proteus bacilli: features and virulence factors].

作者信息

Rózalski Antoni, Kwil Iwona, Torzewska Agnieszka, Baranowska Magdalena, Staczek Paweł

机构信息

Zakład Immunobiologii Bakterii, Instytut Mikrobiologii i Immunologii Uniwersytetu Łódzkiego, Poland.

出版信息

Postepy Hig Med Dosw (Online). 2007;61:204-19.

Abstract

In this article, different aspects of virulence factors of Proteus bacilii (P. mirabilis, P. vulgaris, P. penneri i P. hauseri) are presented. These are opportunistic pathogens that cause different kinds of infections, most frequently of the urinary tract. These bacteria have developed several virulence factors, such as adherence due to the presence of fimbriae or afimbrial adhesins, invasiveness, swarming phenomenon, hemolytic activity, urea hydrolysis, proteolysis, and endotoxicity. Below we focus on data concerning the molecular basis of the pathogenicity of Proteus bacilli.

摘要

本文介绍了变形杆菌属细菌(奇异变形杆菌、普通变形杆菌、彭氏变形杆菌和豪氏变形杆菌)毒力因子的不同方面。这些是引起各种感染的机会致病菌,最常见的是尿路感染。这些细菌已产生了多种毒力因子,如由于菌毛或无纤毛黏附素的存在而导致的黏附、侵袭性、群集现象、溶血活性、尿素水解、蛋白水解和内毒素毒性。下面我们将重点关注有关变形杆菌致病性分子基础的数据。

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