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欧洲心脏手术风险评估系统(EuroSCORE)术前风险预测与冠状动脉旁路移植术后生活质量变化之间的关系。

The relationship between EuroSCORE preoperative risk prediction and quality of life changes after coronary artery by-pass surgery.

作者信息

Peric Vladan, Borzanovic Milorad, Jovanovic Aleksandar, Stolic Radojica, Sovtic Sasa, Trajkovic Goran

机构信息

University of Pristina, Faculty of Medicine, Internal Clinic, Anri Didana bb, 28000 Kosovska Mitrovica, Serbia and Montenegro.

出版信息

Interact Cardiovasc Thorac Surg. 2005 Dec;4(6):622-6. doi: 10.1510/icvts.2005.109546. Epub 2005 Sep 21.

Abstract

OBJECTIVES

To examine the relationship between preoperative risk prediction and the quality of life (QOL) changes six months after coronary artery by-pass surgery (CABG).

METHODS

From February to May 2002, we prospectively studied 243 consecutive patients, who underwent elective CABG. The Nottingham Health Profile Questionnaire (NHP) part 1 was used as the model for QOL determination. We distributed the questionnaire to all patients before CABG and six months after CABG. Two hundred and twenty-six patients filled in the postoperative questionnaire. We calculated the preoperative risk of death using the European System for Cardiac Operative Risk Evaluation (EuroSCORE).

RESULTS

Eighty-nine out of 243 (37%) patients were in low risk group, 108/243 (44%) were in medium risk group and 46/243 (19%) were in high risk group. Prior to CABG, higher EuroSCORE was related to poorer quality of life of the examinees (r=0.23, P<0.001). Six months after the operation, the improvement in QOL was related to higher EuroSCORE in section of energy (r=0.19, P=0.005). To determine the preoperative factors influencing the changes of QOL scores after CABG, we performed logistic regression, first by univariate analysis, and then by multivariate analysis. We analyzed 26 examined variables with potential influence on postoperative QOL. EuroSCORE was not the predictor of the QOL changes six months after CABG.

CONCLUSIONS

Patients with higher EuroSCORE risk of death had worse preoperative QOL. Patients with higher EuroSCORE had greater improvement of QOL in section of energy. EuroSCORE was not the predictor of QOL changes after CABG.

摘要

目的

研究冠状动脉搭桥手术(CABG)术前风险预测与术后六个月生活质量(QOL)变化之间的关系。

方法

2002年2月至5月,我们对243例连续接受择期CABG的患者进行了前瞻性研究。采用诺丁汉健康状况问卷(NHP)第1部分作为生活质量测定模型。在CABG术前和术后六个月,我们向所有患者发放了问卷。226例患者填写了术后问卷。我们使用欧洲心脏手术风险评估系统(EuroSCORE)计算术前死亡风险。

结果

243例患者中,89例(37%)为低风险组,108例(44%)为中风险组,46例(19%)为高风险组。在CABG术前,较高的EuroSCORE与受检者较差的生活质量相关(r=0.23,P<0.001)。术后六个月,生活质量的改善与能量部分较高的EuroSCORE相关(r=0.19,P=0.005)。为了确定影响CABG术后生活质量评分变化的术前因素,我们首先进行单因素分析,然后进行多因素分析。我们分析了26个可能影响术后生活质量的检查变量。EuroSCORE不是CABG术后六个月生活质量变化的预测指标。

结论

EuroSCORE死亡风险较高的患者术前生活质量较差。EuroSCORE较高的患者在能量部分生活质量改善更大。EuroSCORE不是CABG术后生活质量变化的预测指标。

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