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中枢内脂素对雏鸡有促食欲作用。

Central visfatin causes orexigenic effects in chicks.

作者信息

Cline Mark A, Nandar Wint, Prall Brian C, Bowden Christie N, Denbow D Michael

机构信息

Department of Biology (6931), Radford University, Radford, VA 24142, USA.

出版信息

Behav Brain Res. 2008 Jan 25;186(2):293-7. doi: 10.1016/j.bbr.2007.08.016. Epub 2007 Aug 23.

Abstract

Intracerebroventricular injection of visfatin caused increased feed intake and pecking efficiency, but did not affect water intake in chicks. Visfatin-treated chicks had increased c-Fos immunoreactivity in the lateral hypothalamus, decreased reactivity in the ventromedial hypothalamus and the dorsomedial hypothalamus, infundibular nucleus, periventricular nucleus, paraventricular nucleus were not affected. A low dose of visfatin increased locomotion. We conclude that intracerebroventricular injection of visfatin causes orexigenic effects in chicks.

摘要

向雏鸡脑室内注射内脂素会导致采食量和啄食效率增加,但不影响其饮水量。接受内脂素治疗的雏鸡下丘脑外侧的c-Fos免疫反应性增加,下丘脑腹内侧和背内侧、漏斗核、室周核、室旁核的反应性降低。低剂量的内脂素会增加活动能力。我们得出结论,向雏鸡脑室内注射内脂素会产生促食欲作用。

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