[问号钩端螺旋体巴达维亚血清群2株疫苗潜力评估]
[Evaluation of the vaccine potentiality of 2 strains from Leptospira interrogans serogroup Ballum].
作者信息
Rodríguez Andrés González, Jiménez Yoandra Rodríguez, Santiesteban Niurka Batista, Abreu Yolanda Valdés, Osenes Juan Francisco Núñez, González Marta González
机构信息
Instituto Finlay, Centro de Investigación y Producción de Vacunas, Ciudad de La Habana, Cuba.
出版信息
Rev Cubana Med Trop. 2005 Jan-Apr;57(1):63-4.
PMID:17966485
Abstract
Two vacine candidate strains from Ballum serogroup were characterized and their immunogenicity and protective power were studied in hamster. The monovalent vaccine formulations obtained showed a high immunogenicity and capacity of homologous protection and, in a lesser degree, of cross protection.
摘要
对来自巴伦血清群的两种候选疫苗株进行了特性鉴定，并在仓鼠中研究了它们的免疫原性和保护力。所获得的单价疫苗制剂显示出高免疫原性以及同源保护能力，在较小程度上还具有交叉保护能力。
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