Papagiannis John, Maounis Themistoklis, Laskari Cleo, Theodorakis George N, Rammos Spyridon
Paediatric Cardiology Department, Onassis Cardiac Surgery Centre, Athens, Greece.
Hellenic J Cardiol. 2007 Sep-Oct;48(5):268-77.
Atrial tachycardias are a common problem following the surgical repair of complex congenital heart defects (CHD) and have a poor response to medication. The aim of this study was to describe the results of the treatment of such tachycardias with radiofrequency ablation in our hospital.
A retrospective study was performed of the medical records and electronically stored data from electrophysiological studies (EPS) and ablation procedures in patients with atrial tachycardias following the surgical repair of CHD. Established electrophysiological techniques were used in all patients, while newer three-dimensional imaging methods were also employed in some cases. Ablation was carried out using a radiofrequency generator and catheters with a 4-10 mm terminal electrode.
Twenty-two patients aged 11-45 years (30.6 +/- 10.8), including 9 women, underwent an EPS and ablation of atrial tachycardias after the surgical repair of CHD. All had recurrent tachycardias refractory to antiarrhythmic medication. The anatomical diagnoses were tetralogy of Fallot (8), transposition of the great arteries (6), single ventricle (3), and other (5). Most patients had typical atrial flutter and/or incisional atrial reentrant tachycardia. The initial success rate of ablation for all arrhythmias was 88% in patients with tetralogy of Fallot, 83% for transposition of the great arteries, 66% for single ventricle, and 80% for the other diagnoses. Three-dimensional imaging was of significant assistance in mapping and ablation and in reducing the duration of fluoroscopy. Two vascular complications (femoral arteriovenous fistulae) were observed. The tachycardia recurrence rate was 54%. After repeated procedures, 59% of patients were free of arrhythmias and antiarrhythmic medications. No patient with a single ventricle remained free of arrhythmias during follow up, while in the other groups the arrhythmia/drug-free rate was 66-75%. Two patients with unsuccessful ablation died, one from heart failure and the other because of the tachycardia.
Atrial tachycardias in patients with surgically treated CHD are associated with increased morbidity and mortality. Radiofrequency ablation has satisfactory results. In spite of the high relapse rate, a significant number of patients can become free of arrhythmias after repeat procedures.
房性心动过速是复杂先天性心脏病(CHD)手术修复后的常见问题,对药物治疗反应不佳。本研究的目的是描述我院采用射频消融治疗此类心动过速的结果。
对CHD手术修复后发生房性心动过速患者的病历以及电生理研究(EPS)和消融手术的电子存储数据进行回顾性研究。所有患者均采用既定的电生理技术,部分病例还采用了更新的三维成像方法。使用射频发生器和末端电极直径为4 - 10 mm的导管进行消融。
22例年龄在11 - 45岁(30.6 +/- 10.8)的患者,包括9名女性,在CHD手术修复后接受了EPS和房性心动过速消融。所有患者的室上性心动过速对抗心律失常药物均无效。解剖诊断为法洛四联症(8例)、大动脉转位(6例)、单心室(3例)和其他(5例)。大多数患者有典型房扑和/或切口性房性折返性心动过速。法洛四联症患者所有心律失常的初始消融成功率为88%,大动脉转位患者为83%,单心室患者为66%,其他诊断患者为80%。三维成像在标测和消融以及减少透视时间方面有显著帮助。观察到2例血管并发症(股动静脉瘘)。心动过速复发率为54%。重复手术后,59%的患者无心律失常且无需使用抗心律失常药物。随访期间,单心室患者无一例无心律失常,而其他组的心律失常/无药率为66 - 75%。2例消融失败的患者死亡,1例死于心力衰竭,另1例死于心动过速。
接受手术治疗的CHD患者的房性心动过速与发病率和死亡率增加相关。射频消融有令人满意的结果。尽管复发率高,但相当数量的患者在重复手术后可无心律失常。