干细胞与生命速率
Stem cells and the rate of living.
作者信息
Krishnamurthy Janakiraman, Sharpless Norman E
机构信息
Departments of Medicine and Genetics, The Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Departments of Medicine and Genetics, The Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
出版信息
Cell Stem Cell. 2007 Jun 7;1(1):9-11. doi: 10.1016/j.stem.2007.05.004.
The "rate-of-living theory" is an ancient explanation of longevity which holds that aging occurs due to the exhaustion of some finite substance-breaths, heartbeats, etc. While this theory as originally conceived has been debunked, new work (Ruzankina et al. [2007], in this issue of Cell Stem Cell) suggests that mammals in fact do have a finite number of stem cell replications per life.
“生活速率理论”是一种关于长寿的古老解释，该理论认为衰老的发生是由于某种有限物质（气息、心跳等）的耗尽。虽然最初提出的这一理论已被推翻，但新的研究工作（鲁赞基娜等人，《细胞干细胞》本期，2007年）表明，事实上哺乳动物一生中干细胞的复制次数是有限的。
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