Suppr超能文献

[抗精神病吩噻嗪类药物的新生物学特性]

[New biological properties of neuroleptic phenothiazines].

作者信息

Morak-Młodawska Beata, Jeleń Małgorzata

机构信息

Slaski Uniwersytet Medyczny w Katowicach, Katedra i Zakład Chemii Organicznej w Sosnowcu.

出版信息

Pol Merkur Lekarski. 2007 Dec;23(138):459-61.

Abstract

Phenothiazines are the oldest and the largest group of neuroleptic drugs. These compounds are widely used in psychiatry, especially in the treatment of schizophrenia, maniac and delusion disorders. They exhibit valuable antiemetic, antihistaminic and antitussive properties. There have appeared numerous articles for last ten years on new biological properties of phenothiazines, among them anticancer, antibacterial, antiprotozoic, antiviral, antiprionic and multidrug resistance reversal activity. Considering intensive development in the studies on the new activities of phenothiazines it seems to be necessary to organize and clarify the recent knowledge in this field.

摘要

吩噻嗪类是最古老且数量最多的一类抗精神病药物。这些化合物广泛应用于精神病学领域,尤其用于治疗精神分裂症、躁狂症和妄想症。它们具有重要的止吐、抗组胺和镇咳特性。在过去十年中,出现了大量关于吩噻嗪类新生物学特性的文章,其中包括抗癌、抗菌、抗原虫、抗病毒、抗朊病毒和多药耐药逆转活性。鉴于吩噻嗪类新活性研究的密集开展,整理和阐明该领域的最新知识似乎很有必要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验