Saita Asumi, Inoue Ayako, Ishibashi Hisashi, Tominaga Koji, Hori Satoko, Miki Akiko, Ohtani Hisakazu, Ono Nobuaki, Sawada Yasufumi
Fukuoka City Pharmaceutical Association Pharmacy, Tyuo-ku, Fukuoka City, Japan.
Yakugaku Zasshi. 2008 May;128(5):795-803. doi: 10.1248/yakushi.128.795.
Since patients who used brand-name and generic ketoprofen (KP) tapes dispensed in the Fukuoka City Pharmaceutical Association Pharmacy complained of a difference in feeling between the two products, we conducted a questionnaire survey in patients using KP tapes to determine the usability of brand-name and generic tapes. Patients receiving the brand-name KP tape (product A) and/or a generic KP tape (product B) in our pharmacy were interviewed concerning 20 items including 1) dosage regimen, 2) outer package, 3) liner, 4) the tape itself, and 5) condition of application sites. A significant difference in usability between products A and B was observed in 4 of the 20 items evaluated, i.e., 1) easiness of opening of the outer pouch, 2) easiness of removing the liner film, 3) condition of the application site after removal of the tape, and 4) relief of pain in the target lesion after application. As suggested by patients who had complained of a difference in usability between products A and B, the participants in the survey tended to prefer the brand-name KP tape to the generic product. The findings of the survey indicate that when a brand-name product is switched to generic products, pharmacists should evaluate the usability of such products carefully to select those that will ensure proper drug use by patients.
由于在福冈市医药协会药房配发的使用品牌和通用型酮洛芬(KP)贴剂的患者抱怨这两种产品在使用感受上存在差异,我们对使用KP贴剂的患者进行了问卷调查,以确定品牌和通用型贴剂的易用性。在我们药房接受品牌KP贴剂(产品A)和/或通用型KP贴剂(产品B)的患者就包括1)给药方案、2)外包装、3)衬垫、4)贴剂本身以及5)应用部位状况在内的20项内容接受了访谈。在评估的20项内容中的4项中观察到产品A和B在易用性上存在显著差异,即1)外袋打开的容易程度、2)衬垫薄膜去除的容易程度、3)去除贴剂后应用部位的状况以及4)应用后靶病变处疼痛的缓解情况。正如抱怨产品A和B在易用性上存在差异的患者所指出的那样,调查参与者倾向于更喜欢品牌KP贴剂而非通用型产品。调查结果表明,当品牌产品转换为通用型产品时,药剂师应仔细评估此类产品的易用性,以选择能确保患者正确用药的产品。