Sherman Michael G, Flax Michael, Namerow Kenneth, Murray Peter E
Department of Endodontics, Nova Southeastern University, Fort Lauderdale, Florida 33328, USA.
J Endod. 2008 Jun;34(6):656-9. doi: 10.1016/j.joen.2008.02.016. Epub 2008 Apr 25.
The aim of this randomized, double-blinded study was to compare the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine (AE) with 2% lidocaine with 1:100,000 epinephrine (LE) for Gow-Gates blocks and maxillary infiltrations in patients experiencing irreversible pulpitis in mandibular and maxillary posterior teeth. Forty patients diagnosed with irreversible pulpitis of a posterior tooth randomly received either AE or LE by using a Gow-Gates injection or maxillary infiltration. Endodontic access was initiated after no response to Endo-ice 15 minutes after solution deposition. Success was defined as none to mild pain on a visual analogue scale after access. Chi-square and analysis of variance statistical tests were used to analyze the data. Successful endodontic treatment substantially reduced the assessment of pulpitis pain by patients (analysis of variance, P < .0001). Overall anesthetic success in both dental arches was 87.5%. Anesthetic success was not influenced by tooth arch (chi(2), P > .7515) or gender (chi(2), P > .1115). AE proved to be as effective but not superior to LE (P > .6002). These results demonstrated the similar anesthetic effectiveness of AE and LE when used during the endodontic treatment of teeth diagnosed with irreversible pulpitis.
这项随机双盲研究的目的是比较4%阿替卡因加1:100,000肾上腺素(AE)与2%利多卡因加1:100,000肾上腺素(LE)在下颌和上颌后牙患有不可逆性牙髓炎患者中进行Gow-Gates阻滞和上颌浸润麻醉时的麻醉效果。40例被诊断为后牙不可逆性牙髓炎的患者通过Gow-Gates注射或上颌浸润随机接受AE或LE。在溶液注入15分钟后对Endo-ice无反应时开始进行牙髓腔预备。成功的定义为预备后视觉模拟量表上无至轻度疼痛。采用卡方检验和方差分析统计检验来分析数据。成功的牙髓治疗显著降低了患者对牙髓炎疼痛的评估(方差分析,P <.0001)。两个牙弓的总体麻醉成功率为87.5%。麻醉成功率不受牙弓(卡方检验,P >.7515)或性别(卡方检验,P >.1115)的影响。结果证明AE与LE效果相似但并不优于LE(P >.6002)。这些结果表明,在对诊断为不可逆性牙髓炎的牙齿进行牙髓治疗时,AE和LE具有相似的麻醉效果。